首页 > 抗体蛋白 > 抗体
Purified anti-Syk Antibody
产品名称:
Purified anti-Syk Antibody
产品类别:
抗体
产品编号:
646001
产品应用:
646001
[价格]
规格 价格 库存
25µg ¥ 1488 1

产品详情

Product Details

Verified Reactivity
Mouse
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
Mouse Syk peptide aa306-333
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography.
Concentration
0.5 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C.
Application

WB - Quality tested
IP - Reported in the literature, not verified in house

Recommended Usage

Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested use of this reagent is 0.25 - 1.0 ?g per ml. It is recommended that the reagent be titrated for optimal performance for each application.

Application Notes

This product is for in vitro research use only. It is not to be used for commercial purposes. Use of this product to produce products for sale or for diagnostic therapeutic or drug discovery purposes is prohibited. In order to obtain a license to use this product for commercial purposes contact The Regents of the University of California.

Additional Product Notes

In the first WB figure above, the cell lines selected? for antibody testing were chosen to demonstrate specificity and species cross-reactivity, A549 was chosen as a human control cell line that does not express Syk protein; RPMI 8225 and Daudi are human cell lines that express Syk protein; and A20 cells is a mouse cell line that expresses Syk protein. Predicted SYK expression was obtained from Human Protein Atlas.

Application References

(PubMed link indicates BioLegend citation)
  1. Chu D, et al. 1999. J. Immunol. 163:2610.
  2. Ackermann JA, et al. 2015. J Immunol. 194:4650. PubMed
Product Citations
  1. Luo W et al. 2018. Immunity. 48(2):313-326 . PubMed
  2. Ackermann J, et al. 2015. J Immunol. 194:4650. PubMed
  3. Németh T, et al. 2016. Nat Commun. 7: 11004. PubMed
RRID
AB_1659262 (BioLegend Cat. No. 646001) AB_1659261 (BioLegend Cat. No. 646002)

Antigen Details

Structure
Non-receptor associated tyrosine kinase, contains 2 SH2 domains, 72 kD
Distribution

Cytoplasmic protein, widely expressed in hematopoietic cells

Function
Couples immunoreceptor to downstream signaling events that mediate cellular responses including proliferation, differentiation, and phagocytosis
Biology Area
Cell Biology, Signal Transduction
Antigen References

1. Taniguchi T, et al. 1991. J. Biol. Chem. 266:15790.
2. Toyabe SL, et al. 2001.Immunology 103:164.

Gene ID
6850 View all products for this Gene ID
UniProt
View information about Syk on UniProt.org

联系我们

TEL:021-34661275  点击拨打热线