Purified anti-human CD137L (4-1BB Ligand) Antibody
- 产品名称:
- Purified anti-human CD137L (4-1BB Ligand) Antibody
- 产品类别:
- 抗体
- 产品编号:
- 311502
- 产品应用:
- 311502
- Verified Reactivity
- Human
- Reported Reactivity
- African Green, Baboon, Cynomolgus, Rhesus
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤2.0 ?g per million cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.
- Application Notes
For most successful immunofluorescent staining results, it may be important to maximize signal over background by using a relatively bright fluorochrome-antibody conjugate (Cat. No. 311504) or by using a high sensitivity, three-layer staining technique (e.g., including a biotinylated anti-mouse IgG second step (Cat. No. 405303), followed by SAv-PE (Cat. No. 405204)).
- Application References
(PubMed link indicates BioLegend citation) -
- Gullo C,?et al. 2010.?PLoS One. 5:e10845. (FC)?PubMed
- Product Citations
-
- Li M, et al. 2021. J Clin Invest. 131:. PubMed
- Ho W, et al. 2013. Cancer Res. 73:652. PubMed
- Lee-Chang C, et al. 2021. J Exp Med. 218:. PubMed
- Eriksson E, et al. 2017. Clin Cancer Res. 5.018055556. PubMed
- Vidard L, et al. 2019. J Immunol. 203:676. PubMed
- RRID
- AB_314881 (BioLegend Cat. No. 311502)
- Structure
- TNF superfamily, 97 kD
- Distribution
-
Antigen presenting cells, activated B cells and T cells
- Function
- T cell proliferation, cytokine production
- Ligand/Receptor
- 4-1BB (CDw137)
- Cell Type
- Antigen-presenting cells, B cells, T cells
- Biology Area
- Costimulatory Molecules, Immunology
- Molecular Family
- CD Molecules
- Antigen References
-
1. Akiba H,?et al.?2000.?J. Exp. Med.?191:375.?
2. Pollak KE,?et al.?1995.?Eur. J. Immunol.?25:488.?
3. DeBenedette MA,?et al.?1997.?J. Immunol.?158:551.?
4. Goodwin RG,?et al.?1993.?Eur. J. Immunol.?23:2631.
- Gene ID
- 8744 View all products for this Gene ID
- UniProt
- View information about CD137L on UniProt.org