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Purified anti-human CD137L (4-1BB Ligand) Antibody
产品名称:
Purified anti-human CD137L (4-1BB Ligand) Antibody
产品类别:
抗体
产品编号:
311502
产品应用:
311502
[价格]
规格 价格 库存
100µg ¥ 1548 1

产品详情

Product Details

Verified Reactivity
Human
Reported Reactivity
African Green, Baboon, Cynomolgus, Rhesus
Antibody Type
Monoclonal
Host Species
Mouse
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography.
Concentration
0.5 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C.
Application

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤2.0 ?g per million cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.

Application Notes

For most successful immunofluorescent staining results, it may be important to maximize signal over background by using a relatively bright fluorochrome-antibody conjugate (Cat. No. 311504) or by using a high sensitivity, three-layer staining technique (e.g., including a biotinylated anti-mouse IgG second step (Cat. No. 405303), followed by SAv-PE (Cat. No. 405204)).

Application References

(PubMed link indicates BioLegend citation)
  1. Gullo C,?et al. 2010.?PLoS One. 5:e10845. (FC)?PubMed
Product Citations
  1. Li M, et al. 2021. J Clin Invest. 131:. PubMed
  2. Ho W, et al. 2013. Cancer Res. 73:652. PubMed
  3. Lee-Chang C, et al. 2021. J Exp Med. 218:. PubMed
  4. Eriksson E, et al. 2017. Clin Cancer Res. 5.018055556. PubMed
  5. Vidard L, et al. 2019. J Immunol. 203:676. PubMed
RRID
AB_314881 (BioLegend Cat. No. 311502)

Antigen Details

Structure
TNF superfamily, 97 kD
Distribution

Antigen presenting cells, activated B cells and T cells

Function
T cell proliferation, cytokine production
Ligand/Receptor
4-1BB (CDw137)
Cell Type
Antigen-presenting cells, B cells, T cells
Biology Area
Costimulatory Molecules, Immunology
Molecular Family
CD Molecules
Antigen References

1. Akiba H,?et al.?2000.?J. Exp. Med.?191:375.?
2. Pollak KE,?et al.?1995.?Eur. J. Immunol.?25:488.?
3. DeBenedette MA,?et al.?1997.?J. Immunol.?158:551.?
4. Goodwin RG,?et al.?1993.?Eur. J. Immunol.?23:2631.

Gene ID
8744 View all products for this Gene ID
UniProt
View information about CD137L on UniProt.org

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