APC/Fire™ 750 anti-human CD182 (CXCR2) Antib-上海雅吉生物科技有限公司

规格	价格	库存
25tests	￥ 1632	1

Product Details

Verified Reactivity

Human

Antibody Type

Monoclonal

Host Species

Mouse

Immunogen

Human CXCR2 transfected L1.2 cells

Formulation

Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)

Preparation

The antibody was purified by affinity chromatography and conjugated with APC/Fire? 750 under optimal conditions.

Concentration

Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)

Storage & Handling

The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.

Application

FC -?Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 ?l per million cells in 100 ?l staining volume or 5 ?l per 100 ?l of whole blood.

* APC/Fire? 750 has a maximum excitation of 650 nm and a maximum emission of 787 nm.

Excitation Laser

Red Laser (633 nm)

Application Notes

Additional reported applications (for the relevant formats) include: The 5E8/CXCR2 antibody is useful for immunofluorescent staining and flow cytometric analysis of CXCR2 expression.

Application References (PubMed link indicates BioLegend citation)

Kyriakakis E,?et al.?2011.?J Leukoc Biol.?90:929.?PubMed.

Product Citations

Fran?a TT, et al. 2021. JCI Insight. 6:. PubMed

RRID

AB_2734294 (BioLegend Cat. No. 320719) AB_2734295 (BioLegend Cat. No. 320720)

Antigen Details

Structure: Seven transmembrane spanning, G protein-coupled receptor (CPCR), 67-70 kD, homodier or teterodimer with CXCR1
Distribution: Granulocytes, NK cells, subset of T cells, monocytes, endothelial cells, oligodendrocytes
Function: Neutrophil activation, chemotaxis, angiogenesis
Ligand/Receptor: IL-8(CXCL8), NAP-2(CXCL7), GCP-2(CXCL6), GRO-& alpha;,?, γ (CXCL1, CXCL2, CXCL3)
Cell Type: Granulocytes, NK cells, T cells, Monocytes, Endothelial cells, Oligodendrocytes, Neutrophils
Biology Area: Angiogenesis, Cell Biology, Immunology, Neuroinflammation, Neuroscience
Molecular Family: CD Molecules, Cytokine/Chemokine Receptors, GPCR
Antigen References: 1. Chuntharapai A,?et al.?1994.?J. Immunol.?153:5682.
2. Wilson S,?et al.?2005.?J. Biol. Chem.?280:28663.
3. Emadi S,?et al.?2005.?Blood?105:464.
4. Omari KM,?et al.?2005.?Brain?128:1003.
5. Juremalm M and Nilsson G. 2005.?Chem. Immunol. Allergy?87:130.
6. Wolf M,?et al.?1998.?Eur. J. Immunol.?28:164.
Gene ID: 3579 View all products for this Gene ID
UniProt: View information about CD182 on UniProt.org

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