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Alexa Fluor® 647 anti-human CD182 (CXCR2) Anti
产品名称：
Alexa Fluor® 647 anti-human CD182 (CXCR2) Anti
产品类别：
抗体
产品编号：
320714
产品应用：
320714
[价格]
规格 价格 库存
100tests ￥ 3180 1

产品详情

Product Details

Verified Reactivity
Human
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
Human CXCR2 transfected L1.2 cells
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
Preparation
The antibody was purified by affinity chromatography and conjugated with Alexa Fluor? 647 under optimal conditions.
Concentration
Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested
Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 ?l per million cells in 100 ?l staining volume or 5 ?l per 100 ?l of whole blood.

* Alexa Fluor? 647 has a maximum emission of 668 nm when it is excited at 633nm / 635nm.


Alexa Fluor? and Pacific Blue? are trademarks of Life Technologies Corporation.

View full statement regarding label licenses
Excitation Laser
Red Laser (633 nm)
Application Notes

Additional reported applications (for the relevant formats) include: The 5E8/CXCR2 antibody is useful for immunofluorescent staining and flow cytometric analysis of CXCR2 expression.

Application References

(PubMed link indicates BioLegend citation)
  1. Kyriakakis E,?et al.?2011.?J Leukoc Biol.?90:929.?PubMed.
Product Citations
  1. Bratcher P, et al. 2016. J Cystic Fibrosis. 15: 67-73. PubMed
  2. Verma S, et al. 2011. J Immunol. 186:2127. PubMed
  3. Suzuki E, et al. 2016. J Immunol. 197(11):4403-4412. PubMed
  4. Kyriakakis E, et al. 2011. J Leukoc Biol. 90:929. PubMed
RRID
AB_492940 (BioLegend Cat. No. 320714)

Antigen Details

Structure
Seven transmembrane spanning, G protein-coupled receptor (CPCR), 67-70 kD, homodier or teterodimer with CXCR1
Distribution

Granulocytes, NK cells, subset of T cells, monocytes, endothelial cells, oligodendrocytes

Function
Neutrophil activation, chemotaxis, angiogenesis
Ligand/Receptor
IL-8(CXCL8), NAP-2(CXCL7), GCP-2(CXCL6), GRO-& alpha;,?, γ (CXCL1, CXCL2, CXCL3)
Cell Type
Granulocytes, NK cells, T cells, Monocytes, Endothelial cells, Oligodendrocytes, Neutrophils
Biology Area
Angiogenesis, Cell Biology, Immunology, Neuroinflammation, Neuroscience
Molecular Family
CD Molecules, Cytokine/Chemokine Receptors, GPCR
Antigen References

1. Chuntharapai A,?et al.?1994.?J. Immunol.?153:5682.
2. Wilson S,?et al.?2005.?J. Biol. Chem.?280:28663.
3. Emadi S,?et al.?2005.?Blood?105:464.
4. Omari KM,?et al.?2005.?Brain?128:1003.
5. Juremalm M and Nilsson G. 2005.?Chem. Immunol. Allergy?87:130.
6. Wolf M,?et al.?1998.?Eur. J. Immunol.?28:164.

Gene ID
3579 View all products for this Gene ID
UniProt
View information about CD182 on UniProt.org

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