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APC anti-mouse Blimp-1 Antibody
产品名称:
APC anti-mouse Blimp-1 Antibody
产品类别:
抗体
产品编号:
150007
产品应用:
150007
[价格]
规格 价格 库存
25µg ¥ 1788 1

产品详情

Product Details

Verified Reactivity
Mouse
Antibody Type
Monoclonal
Host Species
Rat
Immunogen
Amino acids 255-395 from mouse Blimp-1 fused with GST.
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography and conjugated with APC under optimal conditions.
Concentration
0.2 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

ICFC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by intracellular flow cytometry using our True-Nuclear? Transcription Factor Staining Protocol. For flow cytometric staining, the suggested use of this reagent is ≤ 0.06 ?g per million cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.

Excitation Laser
Red Laser (633 nm)
Application Notes

NOTE: For flow cytometric staining with this clone, True-Nuclear? Transcription Factor Buffer Set (Cat. No. 424401) offers improved staining and is highly recommended.

Product Citations
  1. Marro BS, et al. 2019. Cell Rep. 29:3293. PubMed
  2. Pioli PD, et al. 2020. Immunity. 51(2):351-366. PubMed
  3. Shafiei-Jahani P, et al. 2021. Nat Commun. 12:2526. PubMed
  4. Si J, et al. 2020. Cancer Cell. 38(4):551-566.e11. PubMed
RRID
AB_2728186 (BioLegend Cat. No. 150007) AB_2728187 (BioLegend Cat. No. 150008)

Antigen Details

Structure
Five Kruppel-type zinc finger domains, 98 kD.
Distribution

Plasma cells, CD4+ and CD8+ effector/memory T cells, and natural killer cells.

Function
Terminal differentiation of B cells, effector/memory T cells, role in natural killer cells (NK) and T cell homeostasis, and repressor of BCL6 and c-Myc.
Cell Type
Plasma cells, T cells, NK cells, B cells
Biology Area
Cell Biology, Immunology, Transcription Factors
Antigen References

1. Nakaki F, et al. 2013. Nature 501:222.
2. Crotty S, et al. 2010. Nat. Immunol. 11:114.
3. Zhao WL, et al. 2008. Blood 111:3867.
4. Climmino L, et al. 2008. J. Immunol. 181:2338.
5. Martins, G and Clarne, K. 2008. Annu. Rev. Immunol. 26:133.

Gene ID
12142 View all products for this Gene ID
UniProt
View information about Blimp-1 on UniProt.org

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