PE/Cyanine7 anti-human CD90 (Thy1) Antibody
- 产品名称:
- PE/Cyanine7 anti-human CD90 (Thy1) Antibody
- 产品类别:
- 抗体
- 产品编号:
- 328123
- 产品应用:
- 328123
[价格]
| 规格 |
价格 |
库存 |
| 25tests |
¥ 1764 |
1 |
- Verified Reactivity
- Human
- Reported Reactivity
- African Green, Baboon, Cynomolgus, Pigtailed Macaque, Rhesus, Pig
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- HEL cells
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
- Preparation
- The antibody was purified by affinity chromatography and conjugated with PE/Cyanine7 under optimal conditions.
- Concentration
- Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 ?l per million cells in 100 ?l staining volume or 5 ?l per 100 ?l of whole blood.
- Excitation Laser
- Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
- Application Notes
Clone 5E10 recognizes an epitope on Thy-1 independent of its glycosylation, but is abolished under reducing conditions.4?Additional reported (for the relevant formats) applications include: immunohistochemical staining of acetone-fixed frozen sections, immunoprecipitation1, and immunofluorescence3.
- Additional Product Notes
- BioLegend is in the process of converting the name PE/Cy7 to PE/Cyanine7. The dye molecule remains the same, so you should expect the same quality and performance from our PE/Cyanine7 products. Please contact Technical Service if you have any questions.
- Application References
(PubMed link indicates BioLegend citation) -
- Craig W, et al. 1993. J. Exp. Med. 177:1331. (IP)
- Gundlach CW 4th, et al. 2011. Bioconjug. Chem. 22:1706. (Pig Reactivity)
- Touboul C, et al. 2013. J. Transl. Med. 11:28. (IF)
- Bradley JE, et al. 2013. Lab Invest. 93:365. (Epitope)
- Donnenberg VS, et al. 2010. Cytometry B. Clin. Cytom. 5:287. (IHC)
- Product Citations
-
- Mendt M, et al. 2018. JCI Insight. 9:1523. PubMed
- Chagraoui J, et al. 2021. Cell Stem Cell. 28(1):48-62.e6. PubMed
- Bucan V, et al. 2019. Int J Mol Med. 43:593. PubMed
- Meehan S, et al. 2019. Commun Biol. 2:229. PubMed
- Jenkins RW, et al. 2018. Cancer Discov. 8:196. PubMed
- Celik H, et al. 2021. Cancer Discov. 11:3126. PubMed
- Yankova E, et al. 2021. Nature. 593:597. PubMed
- Hopf A, et al. 2022. Bioengineering (Basel). 9:. PubMed
- Toda H, et al. 2020. Nat Commun. 2.375694444. PubMed
- Saluzzo S, et al. 2022. STAR Protoc. 3:101470. PubMed
- Gray DH, et al. 2022. Mol Ther Nucleic Acids. 27:505. PubMed
- Tomellini E, et al. 2020. Cell Reports. 28(4):1063-1073.e5.. PubMed
- RRID
- AB_2561692 (BioLegend Cat. No. 328123) AB_2561693 (BioLegend Cat. No. 328124)
- Structure
- 25-35 kD glycoprotein, Ig superfamily
- Distribution
-
Subset of CD34+ hematopoietic stem cells, subset of fetal thymocytes, subset of fetal liver cells, fibroblast, activated endothelial cells, neurons and some leukemia cell lines
- Function
- Regulate hematopoiesis and neural cell growth, cell adhesion
- Ligand/Receptor
- β3 integrin, β2 integrin
- Cell Type
- Endothelial cells, Fibroblasts, Hematopoietic stem and progenitors, Leukemia, Mesenchymal Stem Cells, Neurons, Thymocytes
- Biology Area
- Immunology, Stem Cells
- Molecular Family
- CD Molecules
- Antigen References
-
1. McKenzie JL, et al. 1981. J. Immunol. 126:843.
2. Avalos AM, et al. 2002. Biol. Res. 35:231.
3. Wetzel A, et al. 2004. J. Immunol. 172:3850.
- Gene ID
- 7070 View all products for this Gene ID
- UniProt
- View information about CD90 on UniProt.org