PE anti-mouse CD371 (CLEC12A) Antibody
- 产品名称：
- PE anti-mouse CD371 (CLEC12A) Antibody
- 产品类别：
- 抗体
- 产品编号：
- 143403
- 产品应用：
- 143403
- Verified Reactivity
- Mouse
- Antibody Type
- Monoclonal
- Host Species
- Rat
- Immunogen
- CHO expressing mouse CLEC12A
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions.
- Concentration
- 0.2 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.25 ?g per million cells in 100 ?l volume.? It is recommended that the reagent be titrated for optimal performance for each application.
- Excitation Laser
- Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
- Product Citations
-
- Raulf MK, et al. 2019. Cell Rep. 28:30. PubMed
- Omori S, et al. 2021. Cell Reports. 34(6):108734. PubMed
- Scheyltjens I, et al. 2022. Nat Protoc. 17:2354. PubMed
- RRID
- AB_11126747 (BioLegend Cat. No. 143403) AB_11126984 (BioLegend Cat. No. 143404)
- Structure
- Type II C-type lectin family member, 265 aa, 30.7 kD
- Distribution
-
CD8+ dendritic cells (DCs), a proportion of CD8- dendritic cells, plasmacytoid DCs, monocytes, macrophages, granulocytes, B cells
- Function
- Negative regulator of granuocyte and monocyte function
- Interaction
- PTPN6 and PTPN11
- Cell Type
- B cells, Dendritic cells, Embryonic Stem Cells, Granulocytes, Macrophages, Monocytes
- Biology Area
- Costimulatory Molecules, Immunology, Innate Immunity, Stem Cells
- Molecular Family
- CD Molecules
- Antigen References
-
1. Lahoud MH, et al. 2009. J. Immunol. 182:7587.
2. Chen CH, et al. 2006. Blood 107:1459.
3. Marshall AS, et al. 2004. J. Biol. Chem. 279:14792.
- Gene ID
- 232413 View all products for this Gene ID
- UniProt
- View information about CD371 on UniProt.org
