Ultra-LEAF™ Purified anti-human NKp80 Antibo
- 产品名称：
- Ultra-LEAF™ Purified anti-human NKp80 Antibo
- 产品类别：
- 抗体
- 产品编号：
- 346711
- 产品应用：
- 346711
- Verified Reactivity
- Human
- Reported Reactivity
- African Green, Baboon, Cynomolgus, Rhesus
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- Recombinant ectodomain of human NKp80
- Formulation
- 0.2 ?m filtered in phosphate-buffered solution, pH 7.2, containing no preservative. Endotoxin level is < 0.01 EU/?g of the protein (< 0.001 ng/?g of the protein) as determined by the LAL test.
- Preparation
- The Ultra-LEAF? (Low Endotoxin, Azide-Free) antibody was purified by affinity chromatography.
- Concentration
- The antibody is bottled at the concentration indicated on the vial, typically between 2 mg/mL and 3 mg/mL. Older lots may have also been bottled at 1 mg/mL. To obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C. This Ultra-LEAF? solution contains no preservative; handle under aseptic conditions.
- Application
-
FC -?Quality tested
IP, Block -?Reported in the literature, not verified in house
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.5??g per million cells in 100 ?L volume. It is recommended that the reagent be titrated for optimal performance for each application.
- Application References
(PubMed link indicates BioLegend citation) -
- Welte S, et al. 2006. Nat. Immunol. 7:1334.
- Kuttruff S, et al. 2009. Blood 113:358.
- RRID
- AB_2860905 (BioLegend Cat. No. 346711) AB_2860906 (BioLegend Cat. No. 346712)
- Structure
- Type II transmembrane c-type lectin-like receptor, homodimer, 80 kD
- Distribution
-
NK cells, subset of CD8 T and γ/δ T cells
- Ligand/Receptor
- AICL (activation-induced C-type letcin)
- Bioactivity
- induce NK cell-mediated cytolysis and cytokine release
- Cell Type
- NK cells, T cells
- Biology Area
- Costimulatory Molecules, Immunology, Innate Immunity
- Antigen References
-
1. Kuttruff S, et al. 2009. Blood 113:358
2. Vitale M, et al. 2001. Eur. J. Immunol. 31:233
- Gene ID
- 51348 View all products for this Gene ID
- UniProt
- View information about NKp80 on UniProt.org
