Purified anti-Histone H3.1 Phospho (Ser28) Antibod-上海雅吉生物科技有限公司

规格	价格	库存
100µg	￥ 4164	1

规格

价格

库存

100µg

￥ 4164

Product Details

Verified Reactivity: Human
Antibody Type: Monoclonal
Host Species: Rat
Immunogen: Histone H3.1 S28ph peptide (21-39)(ATKAARK(phS)APATGGVKKPH), Freund's complete adjuvant.
Formulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation: The antibody was purified by affinity chromatography.
Concentration: 0.5 mg/mL
Storage & Handling: The antibody solution should be stored undiluted between 2°C and 8°C.
Application: ICFC - Quality tested
WB,?ChIP - Verified
Direct ELISA, ICC?- Reported in the literature, not verified in house
Recommended Usage: Each lot of this antibody is quality control tested by intracellular immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.25 ?g per million cells in 100 ?L?volume. For ChIP applications, the suggested dilution for ChIP application is 1:50-1:100 by volume. For Western blotting, the suggested use of this reagent is 0.5 - 2.0 ?g/mL. It is recommended that the reagent be titrated for optimal performance for each application.
RRID: AB_2616945 (BioLegend Cat. No. 687602)

Structure: H3 is part of the nucleosome, comprised of an octameric complex with H2A, H2B, and H4 proteins.
Distribution: Nucleus.
Function: H3 is a core component of the nucleosome that serves to wrap and compact DNA into chromatin. Therefore, histones limit the accessibility of DNA by providing mechanisms for transcription regulation, DNA repair and replication and chromosomal stability.
Interaction: Two molecules of H3 form a heterotetramer with two molecules of H4.
Biology Area: Cell Biology, Cell Cycle/DNA Replication, Cell Proliferation and Viability
Molecular Family: Phospho-Proteins
Antigen References: 1. Choi HS, et al. 2005. J. Biol. Chem. 280:13545.
2. Goto H, et al. 2002. Genes Cells 7:11.
3. Garcia BA, et al. 2005. Biochemistry 44:13202.
4. Yoshimi T, et al. 2013. Monoclon. Immunodiagn. Immunother. 32:119.
Gene ID: 8350 View all products for this Gene ID
UniProt: View information about Histone H3.1 Phospho Ser28 on UniProt.org