Purified anti-Parkin Antibody
- 产品名称：
- Purified anti-Parkin Antibody
- 产品类别：
- 抗体
- 产品编号：
- 865601
- 产品应用：
- 865601
- Verified Reactivity
- Human, Mouse, Rat
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
WB - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested use of this reagent is 0.5 - 5.0 ?g per ml. It is recommended that the reagent be titrated for optimal performance for each application.
- RRID
- AB_2810777 (BioLegend Cat. No. 865601) AB_2810778 (BioLegend Cat. No. 865602)
- Structure
- Parkin is a 465 amino acid protein with an apparent molecular mass of ~ 52 kD.
- Distribution
-
Tissue Distribution: Brain, heart, testis, and skeletal muscle.
Cellular Distribution: Cytosol, mitochondria, nucleus, and endoplasmic reticulum.
- Function
- Parkin in involved in protein ubiquitination, protein degradation, mitochondria function, and neurodegeneration.
- Interaction
- Ubiquitin, PINK1
- Ligand/Receptor
- BCL2, SYT11, CCNE1, GPR37, RHOT1/MIRO1, MFN1
- Cell Type
- Astrocytes, Microglia, Neurons, Oligodendrocytes
- Biology Area
- Cell Biology, Mitochondrial Function, Neurodegeneration, Neuroinflammation, Protein Misfolding and Aggregation, Ubiquitin/Protein Degradation
- Molecular Family
- Enzymes and Regulators, Ligases
- Antigen References
-
- Tay SP, et al. 2018. J Biol Chem. 285: 29231-29238.
- Pawlyk AC, et al. 2003. J Biol Chem. 278(48):48120-8.
- Gene ID
- 5071 View all products for this Gene ID
- UniProt
- View information about Parkin on UniProt.org
