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HRP anti-Parkin Antibody
产品名称:
HRP anti-Parkin Antibody
产品类别:
抗体
产品编号:
865604
产品应用:
865604
[价格]
规格 价格 库存
100µg ¥ 3732 1

产品详情

Product Details

Verified Reactivity
Human, Mouse, Rat
Antibody Type
Monoclonal
Host Species
Mouse
Formulation
This antibody is provided in 50% glycerol in aqueous buffered solutions with preservatives.
Preparation
The antibody was purified by affinity chromatography and conjugated with HRP under optimal conditions.
Concentration
0.5 mg/mL
Storage & Handling
Upon receipt, the antibody solution should be stored undiluted at -20°C, and protected from prolonged exposure to light.
Application

WB -?Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by western blotting. For western blotting, the suggested use of this reagent is 0.2?- 2.0??g/mL. It is recommended that the reagent be titrated for optimal performance for each application.

RRID
AB_2861096 (BioLegend Cat. No. 865604)

Antigen Details

Structure
Parkin is a 465 amino acid protein with an apparent molecular mass of ~ 52 kD.
Distribution

Tissue Distribution: Brain, heart, testis, and skeletal muscle.
Cellular Distribution: Cytosol, mitochondria, nucleus, and endoplasmic reticulum.

Function
Parkin in involved in protein ubiquitination, protein degradation, mitochondria function, and neurodegeneration.
Interaction
Ubiquitin, PINK1
Ligand/Receptor
BCL2, SYT11, CCNE1, GPR37, RHOT1/MIRO1, MFN1
Cell Type
Astrocytes, Microglia, Neurons, Oligodendrocytes
Biology Area
Cell Biology, Mitochondrial Function, Neurodegeneration, Neuroinflammation, Protein Misfolding and Aggregation, Ubiquitin/Protein Degradation
Molecular Family
Enzymes and Regulators, Ligases
Antigen References
  1. Tay SP, et al. 2018. J Biol Chem. 285: 29231-29238.
  2. Pawlyk AC, et al. 2003. J Biol Chem. 278(48):48120-8.
Gene ID
5071 View all products for this Gene ID
UniProt
View information about Parkin on UniProt.org

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