Purified anti-human CD81 (TAPA-1) Antibody
- 产品名称：
- Purified anti-human CD81 (TAPA-1) Antibody
- 产品类别：
- 抗体
- 产品编号：
- 349501
- 产品应用：
- 349501
- Verified Reactivity
- Human
- Reported Reactivity
- African Green, Baboon, Cynomolgus, Rhesus
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- Human OCI-LY8 cell line
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
FC - Quality tested
WB, IP - Reported in the literature, not verified in house
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.5 ?g per million cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.
- Application Notes
Additional reported applications (for the relevant formats) include: Western Blotting3 and immunoprecipitation2,3.
- Application References
(PubMed link indicates BioLegend citation) -
- Menno C, et al. 2010. J. Clin. Invest. 4:1265.
- Oren R, et al. 1990. Mol. Cell. Biol. 8:4007. (IP)
- Clark K, et al. 2004. J. Biol. Chem. 279(19):19401. (IP, WB)
- Mochida K, et al. 2008. J. Virol. 13:6711.
- Rappa G, et al. 2014. Mol Cancer Res. 12:1840. PubMed
- Product Citations
-
- Ma Y, et al. 2021. Sci Rep. 11:13471. PubMed
- Shi C, et al. 2019. FASEB J. 33:1617. PubMed
- Vrancx C, et al. 2021. Mol Neurobiol. 58:6647. PubMed
- Alcántara‐Hernández M et al. 2017. Immunity. 47(6):1037-1050 . PubMed
- Chetty VK, et al. 2022. Cancers (Basel). 14:. PubMed
- Rodriguez L, et al. 2020. Cell Reports Medicine. 1(5):100078. PubMed
- Desjardins P, et al. 2022. Int J Mol Sci. 23:. PubMed
- Porter RL, et al. 2022. J Clin Invest. :. PubMed
- van der Heide V, et al. 2022. Cell Rep. :110508. PubMed
- Alcántara-Hernández M, et al. 2021. Nat Protoc. 16:4855. PubMed
- Ter-Ovanesyan D, et al. 2021. Elife. 10:. PubMed
- Araki Y, et al. 2021. Front Oncol. 11:667109. PubMed
- Lim K, et al. 2021. J Extracell Vesicles. 10:e12170. PubMed
- Nakai W, et al. 2016. Sci Rep. 6: 33935. PubMed
- Zheng W, et al. 2022. Nat Biomed Eng. 6:979. PubMed
- Rappa G, et al. 2014. Mol Cancer Res. 12:1840. PubMed
- Bachurski D, et al. 2019. J Extracell Vesicles. 8:1596016. PubMed
- Lobastova L, et al. 2021. Frontiers in Cell and Developmental Biology. 9:698503. PubMed
- Shi C, et al. 2020. Biomedicines. 8:00. PubMed
- Kennedy-Darling J, et al. 2021. Eur J Immunol. 51:1262. PubMed
- You Y, et al. 2022. J Extracell Vesicles. 11:e12183. PubMed
- Menck K, et al. 2017. J Extracell Vesicles. 10.1080/20013078.2017.1340745. PubMed
- D?rsam B, et al. 2018. Front Immunol. 7:e34961. PubMed
- Leylek R, et al. 2020. Cell Rep. 32:108180. PubMed
- RRID
- AB_10642023 (BioLegend Cat. No. 349501) AB_10643417 (BioLegend Cat. No. 349502)
- Structure
- 26 kD, type III transmembrane protein, member of the TM4SF tetraspanin family. Complexed with CD82, CD19, CD21, or CD4, CD8.
- Distribution
-
T cells, NK, monocytes, B cells, endothelial and epithelial cells, low on granulocytes.
- Function
- Regulates cell activation and growth and cell aggregation.
- Cell Type
- B cells, Endothelial cells, Epithelial cells, Monocytes, Neural Stem Cells, NK cells, T cells
- Biology Area
- Cell Biology, Immunology, Neuroscience, Neuroscience Cell Markers, Signal Transduction, Stem Cells, Transcription Factors
- Molecular Family
- Adhesion Molecules, CD Molecules
- Antigen References
-
- Menno C, et al. 2010. J. Clin. Invest. 4:1265.
- Fearon D, et al. 1995. Annu. Rev. Immunol. 13:127.
- Wright M, et al. 1994. Immunol. Today 15:588.
- Gene ID
- 975 View all products for this Gene ID
- UniProt
- View information about CD81 on UniProt.org
