FITC anti-mouse Siglec H Antibody -上海雅吉生物科技有限公司

规格	价格	库存
50µg	￥ 1128	1

Product Details

Verified Reactivity

Mouse

Antibody Type

Monoclonal

Host Species

Rat

Immunogen

Siglec-H-Fc recombinant fusion protein

Formulation

Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.

Preparation

The antibody was purified by affinity chromatography, and conjugated with FITC under optimal conditions.

Concentration

0.5 mg/ml

Storage & Handling

The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.

Application

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.25 ?g per 10⁶ cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.

Excitation Laser

Blue Laser (488 nm)

Application References (PubMed link indicates BioLegend citation)

Blasius AL, et al. 2006. J. Immunol. 177:3260.

Product Citations

Han Y et al. 2019. Cell reports. 27(3):835-846 . PubMed
Kuttke M, et al. 2022. Front Immunol. 13:695576. PubMed
Ghilas S, et al. 2021. iScience. 24:103059. PubMed
Leylek R, et al. 2019. Cell Rep. 29:3736. PubMed
Melo-Silva CR, et al. 2021. PLOS Pathogens. 17(5):e1009593. PubMed
Zeis P, et al. 2020. Immunity. 53:775. PubMed
Lam KC, et al. 2021. Cell. 184:5338. PubMed

RRID

AB_1227760 (BioLegend Cat. No. 129603) AB_1227761 (BioLegend Cat. No. 129604)

Antigen Details

Structure: Sialic acid-binding immunoglobulin-like lectins
Distribution: Siglec-H is expressed exclusively on natural interferon-producing cells (IPCs), also called plasmacytoid dendritic cells in spleen, blood and lymph nodes. The IPCs are characterized by a complex phenotype (CD11c+, Ly-6C+, B220+, CD11b-, CD8+/-).
Function: Siglec-H associates with adaptor protein DAP12 for cell signaling, which reduces type 1 IFN response of IPC to CpG.
Ligand/Receptor: Sialic acid
Cell Type: Dendritic cells
Biology Area: Cell Biology, Immunology, Neuroscience, Neuroscience Cell Markers
Molecular Family: CD Molecules, Siglec Molecules
Antigen References: 1. Blasius AL, et al. 2006. Blood 107:2474.
2. Zhang J, et al. 2006. Blood 107:3600.
3. Blasius AL, et al. 2007. J. Exp. Med. 204:2561.
Gene ID: 233274 View all products for this Gene ID
UniProt: View information about Siglec H on UniProt.org

上海细胞库

原代细胞

细胞培养

细胞服务

酶联试剂盒

生化试剂盒

PCR试剂盒

抗体蛋白

试剂耗材

首页 > 抗体蛋白 > 抗体

产品详情

Product Details

Antigen Details

联系我们