Biotin anti-human APRIL (TNFSF13, CD256) Antibody -上海雅吉生物科技有限公司

规格	价格	库存
50µg	￥ 1488	1

Product Details

Verified Reactivity: Human
Antibody Type: Monoclonal
Host Species: Mouse
Immunogen: His-cohesin-C-terminal APRIL ectodomain
Formulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation: The antibody was purified by affinity chromatography, and conjugated with biotin under optimal conditions.
Concentration: 0.5 mg/ml
Storage & Handling: The antibody solution should be stored undiluted between 2°C and 8°C. Do not freeze.
Application: ELISA Detection - Quality tested
Recommended Usage: Each lot of this antibody is quality control tested by?ELISA assay. For sandwich ELISA detection applications, a concentration range of 0.5-2 ?g/ml is recommended when used in conjunction with purified 33H5 (Cat. No. 524802) as the capture antibody, and recombinant human APRIL (TNFSF13) (ELISA Std.) (Cat. No. 591309) as the protein standard. It is recommended that the reagent be titrated for optimal performance for each application.
Application Notes: Clone 53E11 reacts with recombinant APRIL homotrimer and recombinant APRIL-BAFF heterotrimer.
RRID: AB_2562635 (BioLegend Cat. No. 524903) AB_2562636 (BioLegend Cat. No. 524904)

Antigen Details

Structure: Transmembrane protein of 26 kD, forms a homotrimer that is cleaved from the cell surface resulting in the soluble form of APRIL; forms heterotrimers with BLyS (BAFF)
Distribution: T cells, B cells, dendritic cells, monocytes, and macrophages
Function: Induces proliferation of T and B cells, promotes IgA class switching and downregulates T-cell dependent antibody responses, regulates the growth of a variety of tumor cells
Ligand/Receptor: TNFRSF13b (TACI), TNFRSF17 (BCMA)
Cell Type: T cells, B cells, Dendritic cells, Monocytes, Macrophages
Biology Area: Apoptosis/Tumor Suppressors/Cell Death, Cell Biology, Signal Transduction
Molecular Family: Cytokines/Chemokines
Antigen References: 1. Hymowitz, S, et al. 2005. J. Biol. Chem. 280:7218.
2. Ingold K, et al. 2005. J. Exp. Med. 201:1375.
3. Good K, et al. 2009. J. Immunol. 182:890.
4. Bossen C, et al. 2008. Blood 111:1004.
5. Bossen C, et al. 2006. J. Biol. Chem. 281:13964.
6. Pradet-Balade B, et al. 2002. EMBO J. 21:5711.
7. Hahne M, et al. 1998. J. Exp. Med. 188:1185.
8. Medema JP, et al. 2003. Cell Death Differ. 10:1121.
9. Planelles L, et al. 2007. Haematologica. 92:1284.
10. Dillon SR, et al. 2010. Arthritis Res. Ther 12:R48.
11. Wallweber H, et al. 2004. J. Mol. Biol. 343:283.
12. Chen Y, et al. 2011. PLoS ONE 6:e22202.
13. Roschke V, et al. 2002. J. Immunol. 169:4314.
Gene ID: 8741 View all products for this Gene ID
UniProt: View information about APRIL on UniProt.org

上海细胞库

原代细胞

细胞培养

细胞服务

酶联试剂盒

生化试剂盒

PCR试剂盒

抗体蛋白

试剂耗材

首页 > 抗体蛋白 > 抗体

产品详情

Product Details

Antigen Details

联系我们