Purified anti-mouse CD5 Antibody
- 产品名称:
- Purified anti-mouse CD5 Antibody
- 产品类别:
- 抗体
- 产品编号:
- 100602
- 产品应用:
- 100602
- Verified Reactivity
- Mouse
- Antibody Type
- Monoclonal
- Host Species
- Rat
- Immunogen
- Mouse thymus or spleen
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
FC - Quality tested
IHC-F, CyTOF? - Verified
IHC-P, IP - Reported in the literature, not verified in house
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 ?g per million cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.
- Application Notes
Additional reported applications (for the relevant formats) include: immunoprecipitation1, and immunohistochemistry2 of acetone-fixed frozen tissue sections, zinc-fixed paraffin-embedded sections and formalin-fixed paraffin-embedded sections.
- Application References
(PubMed link indicates BioLegend citation) -
- Ledbetter JA, et al. 1979. Immunol. Rev. 47:63. (IP)
- Ledbetter JA, et al. 1980. J. Exp. Med. 152:280. (FC, IHC)
- Bourdeau A, et al. 2007. Blood doi:10.1182/blood-2006-08-044370.
- Product Citations
-
- Michela Miani et al. 2018. Cell metabolism. 28(4):557-572 . PubMed
- Khan KA, et al. 2020. NPJ Breast Cancer. 6:29. PubMed
- Seifert HA, et al. 2018. Metab Brain Dis. 33:1599. PubMed
- Prado C, et al. 2021. J Neuroinflammation. 18:292. PubMed
- Niss Arfelt K, et al. 2017. Blood. 129:866. PubMed
- Peng V, et al. 2020. J Biol Chem. 295:14866. PubMed
- Doorduijn EM, et al. 2018. Front Immunol. 0.416666667. PubMed
- Khan KA, et al. 2020. NPJ Breast Cancer. 6:29. PubMed
- Formaglio P, et al. 2021. Immunity. 54:2724. PubMed
- Liu H, et al. 2020. J Immunol. 205:1207. PubMed
- Sprouse ML, et al. 2018. JCI Insight. 3:e97322. PubMed
- Lee JY, et al. 2018. Front Immunol. 0.678472222. PubMed
- Yates K, et al. 2018. Proc Natl Acad Sci U S A. 115:2162. PubMed
- Wang HC, et al. 2017. J Immunol. 198:3149. PubMed
- Parigi SM, et al. 2018. Sci Rep. 0.440277778. PubMed
- Kawabe T, et al. 2017. Sci Immunol. 2:eaam9315. PubMed
- Mohrin M, et al. 2021. Aging Cell. 20:e13313. PubMed
- Goltsev Y et al. 2018. Cell. 174(4):968-981 . PubMed
- Cole C, et al. 2018. Nucleic Acids Res. 46:e62. PubMed
- Yamashita M, et al. 2019. Cell Stem Cell. 25:357. PubMed
- K?stele V, et al. 2021. Mucosal Immunol. 14:717. PubMed
- RRID
- AB_312731 (BioLegend Cat. No. 100602)
- Structure
- Member of the scavenger receptor cysteine-rich protein superfamily (SRCR), 67 kD
- Distribution
-
Thymocytes, T cells, B-1 cells
- Function
- Negative regulator of T-B cell interaction
- Ligand/Receptor
- CD72, gp35-37
- Cell Type
- B cells, T cells, Thymocytes
- Biology Area
- Costimulatory Molecules, Immunology
- Molecular Family
- CD Molecules
- Antigen References
-
1. Barclay A, et al. 1997. The Leukocyte Antigen FactsBook Academic Press.
2. Kipps TJ. 1988. Adv. Immunol. 47:117.
3. Antin JH, et al. 1985. J. Immunol. 136:505.
4. Tarakhovsky A, et al. 1995. Science 269:535.
- Gene ID
- 12507 View all products for this Gene ID
- UniProt
- View information about CD5 on UniProt.org