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Purified anti-mouse CD5 Antibody
产品名称:
Purified anti-mouse CD5 Antibody
产品类别:
抗体
产品编号:
100602
产品应用:
100602
[价格]
规格 价格 库存
500µg ¥ 2280 1

产品详情

Product Details

Verified Reactivity
Mouse
Antibody Type
Monoclonal
Host Species
Rat
Immunogen
Mouse thymus or spleen
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography.
Concentration
0.5 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C.
Application

FC - Quality tested
IHC-F, CyTOF? - Verified
IHC-P, IP - Reported in the literature, not verified in house

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 ?g per million cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.

Application Notes

Additional reported applications (for the relevant formats) include: immunoprecipitation1, and immunohistochemistry2 of acetone-fixed frozen tissue sections, zinc-fixed paraffin-embedded sections and formalin-fixed paraffin-embedded sections.

Application References

(PubMed link indicates BioLegend citation)
  1. Ledbetter JA, et al. 1979. Immunol. Rev. 47:63. (IP)
  2. Ledbetter JA, et al. 1980. J. Exp. Med. 152:280. (FC, IHC)
  3. Bourdeau A, et al. 2007. Blood doi:10.1182/blood-2006-08-044370.
Product Citations
  1. Michela Miani et al. 2018. Cell metabolism. 28(4):557-572 . PubMed
  2. Khan KA, et al. 2020. NPJ Breast Cancer. 6:29. PubMed
  3. Seifert HA, et al. 2018. Metab Brain Dis. 33:1599. PubMed
  4. Prado C, et al. 2021. J Neuroinflammation. 18:292. PubMed
  5. Niss Arfelt K, et al. 2017. Blood. 129:866. PubMed
  6. Peng V, et al. 2020. J Biol Chem. 295:14866. PubMed
  7. Doorduijn EM, et al. 2018. Front Immunol. 0.416666667. PubMed
  8. Khan KA, et al. 2020. NPJ Breast Cancer. 6:29. PubMed
  9. Formaglio P, et al. 2021. Immunity. 54:2724. PubMed
  10. Liu H, et al. 2020. J Immunol. 205:1207. PubMed
  11. Sprouse ML, et al. 2018. JCI Insight. 3:e97322. PubMed
  12. Lee JY, et al. 2018. Front Immunol. 0.678472222. PubMed
  13. Yates K, et al. 2018. Proc Natl Acad Sci U S A. 115:2162. PubMed
  14. Wang HC, et al. 2017. J Immunol. 198:3149. PubMed
  15. Parigi SM, et al. 2018. Sci Rep. 0.440277778. PubMed
  16. Kawabe T, et al. 2017. Sci Immunol. 2:eaam9315. PubMed
  17. Mohrin M, et al. 2021. Aging Cell. 20:e13313. PubMed
  18. Goltsev Y et al. 2018. Cell. 174(4):968-981 . PubMed
  19. Cole C, et al. 2018. Nucleic Acids Res. 46:e62. PubMed
  20. Yamashita M, et al. 2019. Cell Stem Cell. 25:357. PubMed
  21. K?stele V, et al. 2021. Mucosal Immunol. 14:717. PubMed
RRID
AB_312731 (BioLegend Cat. No. 100602)

Antigen Details

Structure
Member of the scavenger receptor cysteine-rich protein superfamily (SRCR), 67 kD
Distribution

Thymocytes, T cells, B-1 cells

Function
Negative regulator of T-B cell interaction
Ligand/Receptor
CD72, gp35-37
Cell Type
B cells, T cells, Thymocytes
Biology Area
Costimulatory Molecules, Immunology
Molecular Family
CD Molecules
Antigen References

1. Barclay A, et al. 1997. The Leukocyte Antigen FactsBook Academic Press.
2. Kipps TJ. 1988. Adv. Immunol. 47:117.
3. Antin JH, et al. 1985. J. Immunol. 136:505.
4. Tarakhovsky A, et al. 1995. Science 269:535.

Gene ID
12507 View all products for this Gene ID
UniProt
View information about CD5 on UniProt.org

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