PE/Cyanine7 anti-mouse CD5 Antibody
- 产品名称：
- PE/Cyanine7 anti-mouse CD5 Antibody
- 产品类别：
- 抗体
- 产品编号：
- 100621
- 产品应用：
- 100621
- Verified Reactivity
- Mouse
- Antibody Type
- Monoclonal
- Host Species
- Rat
- Immunogen
- Mouse thymus or spleen
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography and conjugated with PE/Cyanine7 under optimal conditions.
- Concentration
- 0.2 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.25 ?g per million cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.
- Excitation Laser
- Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
- Application Notes
Additional reported applications (for the relevant formats) include: immunoprecipitation1, and immunohistochemistry2 of acetone-fixed frozen tissue sections, zinc-fixed paraffin-embedded sections and formalin-fixed paraffin-embedded sections.
- Additional Product Notes
- BioLegend is in the process of converting the name PE/Cy7 to PE/Cyanine7. The dye molecule remains the same, so you should expect the same quality and performance from our PE/Cyanine7 products. Please contact Technical Service if you have any questions.
- Application References
(PubMed link indicates BioLegend citation) -
- Ledbetter JA, et al. 1979. Immunol. Rev. 47:63. (IP)
- Ledbetter JA, et al. 1980. J. Exp. Med. 152:280. (FC, IHC)
- Bourdeau A, et al. 2007. Blood doi:10.1182/blood-2006-08-044370.
- Product Citations
-
- Fan L, et al. 2020. J Immunol Res. 2020:3032425. PubMed
- Lentucci C, et al. 2017. J Biol Chem. 292:2754-2772. PubMed
- Lehmann-Horn K, et al. 2016. Neurol Neuroimmunol Neuroinflamm. 3: e212. PubMed
- Wang X, et al. 2016. PLoS Pathog. 12: 1005367. PubMed
- Lutes LK, et al. 2021. eLife. 10:00. PubMed
- Bartleson JM, et al. 2020. Nat Immunol. 1384:21. PubMed
- Das S, et al. 2019. Oncogene. 383316. PubMed
- Emg?rd J, et al. 2018. Immunity. 143:419. PubMed
- Yang L, et al. 2021. Cell Death Differ. 28:2616. PubMed
- Zhu Y, et al. 2022. Clin Transl Med. 12:e887. PubMed
- Duan H, et al. 2021. J Clin Invest. 131:. PubMed
- Shibad V, et al. 2021. Front Immunol. 12:722451. PubMed
- Gomez S, et al. 2022. J Immunother Cancer. 10:. PubMed
- Li Z, et al. 2020. J Immunol. 2589:204. PubMed
- Kimura S, et al. 2020. Am J Transplant. 20:977. PubMed
- Xu Y, et al. 2021. iScience. 24:103445. PubMed
- Mao C, et al. 2020. Antib Ther. 0.234027778. PubMed
- Goc J, et al. 2021. Cell. :. PubMed
- RRID
- AB_2562772 (BioLegend Cat. No. 100621) AB_2562773 (BioLegend Cat. No. 100622)
- Structure
- Member of the scavenger receptor cysteine-rich protein superfamily (SRCR), 67 kD
- Distribution
-
Thymocytes, T cells, B-1 cells
- Function
- Negative regulator of T-B cell interaction
- Ligand/Receptor
- CD72, gp35-37
- Cell Type
- B cells, T cells, Thymocytes
- Biology Area
- Costimulatory Molecules, Immunology
- Molecular Family
- CD Molecules
- Antigen References
-
1. Barclay A, et al. 1997. The Leukocyte Antigen FactsBook Academic Press.
2. Kipps TJ. 1988. Adv. Immunol. 47:117.
3. Antin JH, et al. 1985. J. Immunol. 136:505.
4. Tarakhovsky A, et al. 1995. Science 269:535.
- Gene ID
- 12507 View all products for this Gene ID
- UniProt
- View information about CD5 on UniProt.org
