FITC anti-mouse CD5 Antibody
- 产品名称：
- FITC anti-mouse CD5 Antibody
- 产品类别：
- 抗体
- 产品编号：
- 100605
- 产品应用：
- 100605
- Verified Reactivity
- Mouse
- Antibody Type
- Monoclonal
- Host Species
- Rat
- Immunogen
- Mouse thymus or spleen
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography, and conjugated with FITC under optimal conditions.
- Concentration
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤1.0 ?g per million cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.
- Excitation Laser
- Blue Laser (488 nm)
- Application Notes
Additional reported applications (for the relevant formats) include: immunoprecipitation1, and immunohistochemistry2 of acetone-fixed frozen tissue sections, zinc-fixed paraffin-embedded sections and formalin-fixed paraffin-embedded sections.
- Application References
(PubMed link indicates BioLegend citation) -
- Ledbetter JA, et al. 1979. Immunol. Rev. 47:63. (IP)
- Ledbetter JA, et al. 1980. J. Exp. Med. 152:280. (FC, IHC)
- Bourdeau A, et al. 2007. Blood doi:10.1182/blood-2006-08-044370.
- Product Citations
-
- Huang Z et al. 2017. Cell metabolism. 26(3):493-508 . PubMed
- Alotaibi F, et al. 2021. Front Immunol. 11:584937. PubMed
- Lutes LK, et al. 2021. eLife. 10:00. PubMed
- Ganeshan K et al. 2019. Cell. 177(2):399-413 . PubMed
- Solanki A, et al. 2018. Development. 145. PubMed
- Comazzetto S et al. 2018. Cell stem cell. 24(3):477-486 . PubMed
- Mues M, et al. 2019. Cell Rep. 27:631. PubMed
- Kruta M, et al. 2021. Cell Stem Cell. :. PubMed
- Ishikawa E, et al. 2016. Nat Commun. 7: 12756. PubMed
- Kondo M, et al. 2016. J Immunol. 196: 563 - 572. PubMed
- Shiozawa S, et al. 2022. iScience. 25:103537. PubMed
- Nowlan B, et al. 2019. Haematologica. 105:71. PubMed
- Vacca F, et al. 2020. eLife. 9:e54017.. PubMed
- Baomei Wang et al. 2019. Cell reports. 26(6):1614-1626 . PubMed
- Adachi Y, et al. 2019. Nat Commun. 10:3883. PubMed
- Yin S et al. 2019. Cancer cell. 35(2):283-296 . PubMed
- Chen C, et al. 2020. Cell Rep. 2136:30. PubMed
- Clemente–Casares X, et al. 2017. Immunity. 47:974. PubMed
- Magee JA, et al. 2021. Stem Cell Reports. 16:20. PubMed
- DeVilbiss AW, et al. 2021. eLife. 10:00. PubMed
- Li K, et al. 2020. Nat Commun. 0.795138889. PubMed
- Hidalgo San Jose L, et al. 2020. Cell Rep. 30:69. PubMed
- Goldberg EL, et al. 2021. Cell Metabolism. :. PubMed
- Campbell J, et al. 2010. J Immunol. 185:28:00. PubMed
- Gu Z, et al. 2021. Nat Genet. 53:672. PubMed
- Deniset JF et al. 2019. Immunity. 51(1):131-140 . PubMed
- RRID
- AB_312734 (BioLegend Cat. No. 100605) AB_312735 (BioLegend Cat. No. 100606)
- Structure
- Member of the scavenger receptor cysteine-rich protein superfamily (SRCR), 67 kD
- Distribution
-
Thymocytes, T cells, B-1 cells
- Function
- Negative regulator of T-B cell interaction
- Ligand/Receptor
- CD72, gp35-37
- Cell Type
- B cells, T cells, Thymocytes
- Biology Area
- Costimulatory Molecules, Immunology
- Molecular Family
- CD Molecules
- Antigen References
-
1. Barclay A, et al. 1997. The Leukocyte Antigen FactsBook Academic Press.
2. Kipps TJ. 1988. Adv. Immunol. 47:117.
3. Antin JH, et al. 1985. J. Immunol. 136:505.
4. Tarakhovsky A, et al. 1995. Science 269:535.
- Gene ID
- 12507 View all products for this Gene ID
- UniProt
- View information about CD5 on UniProt.org
