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Purified anti-human CD167a (DDR1) Antibody
产品名称:
Purified anti-human CD167a (DDR1) Antibody
产品类别:
抗体
产品编号:
334002
产品应用:
334002
[价格]
规格 价格 库存
100µg ¥ 2472 1

产品详情

Product Details

Verified Reactivity
Human
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
NIH-3T3 cells transfected with human DDR1 (CD167a)
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography.
Concentration
0.5 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C.
Application

FC - Quality tested
IP - Reported in the literature, not verified in house

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤2.0 ?g per million cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.

Application Notes

Additional reported (for the relevant formats) applications include:immunoprecipitation.

RRID
AB_1134243 (BioLegend Cat. No. 334002)

Antigen Details

Structure
Membrane Type II receptor kinase, containing a factor VIII-like domain. Three isoforms have been reported. Predicted molecular weights are: isoform 1, approximately 101.5 kD, isoform 2, approximately 101 kD, and isoform 3 approximately 97 kD.
Distribution

Epithelial cells, keratinocytes, and activated leukocytes. Overexpressed in some breast carcinomas. Expression can be upregulated by p53.

Function
Receptor membrane tyrosine kinase. May be involved in arterial wound repair.
Interaction
CD167a has been reported to interact with a variety of proteins including collagen type II alpha 1, collagen type III alpha 1, collagen type V alpha 2, collagen type XI alpha 1, phospholipase gamma 1, SHC, lipid-anchored docking protein FRS2
Modification
Phosphorylation (Y513)
Cell Type
Epithelial cells, Leukocytes
Biology Area
Immunology
Molecular Family
Adhesion Molecules, CD Molecules
Antigen References

1. DiMarco E, et al. 1993. J. Biol. Chem. 268:24290.
2. Hou G, et al. 2001. J. Clin. Invest. 107:727.
3. Johnson JD, et al. 1993. Proc. Natl. Acad. Sci. USA 90:5677.
4. Sakuma S, et al. 1996. FEBS Lett. 398:165.

Gene ID
780 View all products for this Gene ID
UniProt
View information about CD167a on UniProt.org

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