Purified anti-human CD167a (DDR1) Antibody
- 产品名称:
- Purified anti-human CD167a (DDR1) Antibody
- 产品类别:
- 抗体
- 产品编号:
- 334002
- 产品应用:
- 334002
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- NIH-3T3 cells transfected with human DDR1 (CD167a)
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
FC - Quality tested
IP - Reported in the literature, not verified in house
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤2.0 ?g per million cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.
- Application Notes
Additional reported (for the relevant formats) applications include:immunoprecipitation.
- RRID
- AB_1134243 (BioLegend Cat. No. 334002)
- Structure
- Membrane Type II receptor kinase, containing a factor VIII-like domain. Three isoforms have been reported. Predicted molecular weights are: isoform 1, approximately 101.5 kD, isoform 2, approximately 101 kD, and isoform 3 approximately 97 kD.
- Distribution
-
Epithelial cells, keratinocytes, and activated leukocytes. Overexpressed in some breast carcinomas. Expression can be upregulated by p53.
- Function
- Receptor membrane tyrosine kinase. May be involved in arterial wound repair.
- Interaction
- CD167a has been reported to interact with a variety of proteins including collagen type II alpha 1, collagen type III alpha 1, collagen type V alpha 2, collagen type XI alpha 1, phospholipase gamma 1, SHC, lipid-anchored docking protein FRS2
- Modification
- Phosphorylation (Y513)
- Cell Type
- Epithelial cells, Leukocytes
- Biology Area
- Immunology
- Molecular Family
- Adhesion Molecules, CD Molecules
- Antigen References
-
1. DiMarco E, et al. 1993. J. Biol. Chem. 268:24290.
2. Hou G, et al. 2001. J. Clin. Invest. 107:727.
3. Johnson JD, et al. 1993. Proc. Natl. Acad. Sci. USA 90:5677.
4. Sakuma S, et al. 1996. FEBS Lett. 398:165.
- Gene ID
- 780 View all products for this Gene ID
- UniProt
- View information about CD167a on UniProt.org