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PE anti-human CD167a (DDR1) Antibody
产品名称:
PE anti-human CD167a (DDR1) Antibody
产品类别:
抗体
产品编号:
334005
产品应用:
334005
[价格]
规格 价格 库存
25tests ¥ 1608 1

产品详情

Product Details

Verified Reactivity
Human
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
NIH-3T3 cells transfected with human DDR1 (CD167a)
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
Preparation
The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions.
Concentration
Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 ?l per million cells in 100 ?l staining volume or 5 ?l per 100 ?l of whole blood.

Excitation Laser
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
Application Notes

Additional reported (for the relevant formats) applications include:immunoprecipitation.

Application References

(PubMed link indicates BioLegend citation)
  1. Rudra-Ganguly N, et al. 2014. PLoS One. 9:111515. PubMed
Product Citations
  1. Rudra-Ganguly N, et al. 2014. PLoS One. 9:111515. PubMed
RRID
AB_2261656 (BioLegend Cat. No. 334005) AB_2092093 (BioLegend Cat. No. 334006)

Antigen Details

Structure
Membrane Type II receptor kinase, containing a factor VIII-like domain. Three isoforms have been reported. Predicted molecular weights are: isoform 1, approximately 101.5 kD, isoform 2, approximately 101 kD, and isoform 3 approximately 97 kD.
Distribution

Epithelial cells, keratinocytes, and activated leukocytes. Overexpressed in some breast carcinomas. Expression can be upregulated by p53.

Function
Receptor membrane tyrosine kinase. May be involved in arterial wound repair.
Interaction
CD167a has been reported to interact with a variety of proteins including collagen type II alpha 1, collagen type III alpha 1, collagen type V alpha 2, collagen type XI alpha 1, phospholipase gamma 1, SHC, lipid-anchored docking protein FRS2
Modification
Phosphorylation (Y513)
Cell Type
Epithelial cells, Leukocytes
Biology Area
Immunology
Molecular Family
Adhesion Molecules, CD Molecules
Antigen References

1. DiMarco E, et al. 1993. J. Biol. Chem. 268:24290.
2. Hou G, et al. 2001. J. Clin. Invest. 107:727.
3. Johnson JD, et al. 1993. Proc. Natl. Acad. Sci. USA 90:5677.
4. Sakuma S, et al. 1996. FEBS Lett. 398:165.

Gene ID
780 View all products for this Gene ID
UniProt
View information about CD167a on UniProt.org

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