PE anti-human CD1d Antibody
- 产品名称：
- PE anti-human CD1d Antibody
- 产品类别：
- 抗体
- 产品编号：
- 350305
- 产品应用：
- 350305
[价格]
| 规格 |
价格 |
库存 |
| 25tests |
￥ 1548 |
1 |
- Verified Reactivity
- Human
- Reported Reactivity
- Cynomolgus
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- Human CD1d-Fc fusion
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
- Preparation
- The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions.
- Concentration
- Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 ?l per million cells in 100 ?l staining volume or 5 ?l per 100 ?l of whole blood.
- Excitation Laser
- Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
- Application Notes
Additional reported application (for the relevant formats) include: immunohistochemical staining of frozen tissue sections1, Western blotting1,2, and induction of IL-12 production by crosslinking of CD1d3.
- Application References
(PubMed link indicates BioLegend citation) -
- Exley M, et al. 2000. Immunology 100:37. (IHC, WB)
- Durante-Mangoni E, et al. 2004. J. Immunol. 173:2159. (WB)
- Yue SC, et al. 2005. P. Natl. Acad. Sci. USA 102:11811. (Stim)
- RRID
- AB_10642028 (BioLegend Cat. No. 350305) AB_10641845 (BioLegend Cat. No. 350306)
- Structure
- MHC-like, type I transmembrane protein, member of the CD1 family and the immunoglobulin superfamily
- Distribution
-
Expressed by cortical thymocytes, monocytes, macrophages, dendritic cells, B cells (highly expressed on marginal zone B cells in particular), and in some non-lymphoid cells
- Function
- Present lipid antigens to iNKT cells
- Ligand/Receptor
- When loaded with a lipid, is recognized by the Vα14i TCR from iNKT cells
- Cell Type
- B cells, Dendritic cells, Macrophages, Monocytes, Thymocytes
- Biology Area
- Immunology, Innate Immunity
- Molecular Family
- CD Molecules, MHC Antigens, TCRs
- Antigen References
-
1. Koch M, et al. 2005. Nat. Immunol. 6:819.
2. Liu X, et al. 2010. P. Natl. Acad. Sci. USA 107:13010.
3. Zeissig S, et al. 2010. J. Clin. Invest. 120:2889.
4. Teige A, et al. 2010. J. Immunol. 185:345.
- Gene ID
- 912 View all products for this Gene ID
- UniProt
- View information about CD1d on UniProt.org
