Brilliant Violet 421™ anti-human CD1d Antibo
- 产品名称：
- Brilliant Violet 421™ anti-human CD1d Antibo
- 产品类别：
- 抗体
- 产品编号：
- 350315
- 产品应用：
- 350315
[价格]
| 规格 |
价格 |
库存 |
| 25tests |
￥ 2184 |
1 |
- Verified Reactivity
- Human
- Reported Reactivity
- Cynomolgus
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- Human CD1d-Fc fusion
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
FC -?Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 ?l per million cells in 100 ?l staining volume or 5 ?l per 100 ?l of whole blood.
Learn more about Brilliant Violet?.
This product is subject to proprietary rights of Sirigen Inc. and is made and sold under license from Sirigen Inc. The purchase of this product conveys to the buyer a non-transferable right to use the purchased product for research purposes only. This product may not be resold or incorporated in any manner into another product for resale. Any use for therapeutics or diagnostics is strictly prohibited. This product is covered by U.S. Patent(s), pending patent applications and foreign equivalents. - Excitation Laser
- Violet Laser (405 nm)
- Application Notes
Additional reported application (for the relevant formats) include: immunohistochemical staining of frozen tissue sections1, Western blotting1,2, and induction of IL-12 production by crosslinking of CD1d3.
- Application References
(PubMed link indicates BioLegend citation) -
- Exley M, et al. 2000. Immunology 100:37. (IHC, WB)
- Durante-Mangoni E, et al. 2004. J. Immunol. 173:2159. (WB)
- Yue SC, et al. 2005. P. Natl. Acad. Sci. USA 102:11811. (Stim)
- RRID
- AB_2687378 (BioLegend Cat. No. 350315) AB_2687379 (BioLegend Cat. No. 350316)
- Structure
- MHC-like, type I transmembrane protein, member of the CD1 family and the immunoglobulin superfamily
- Distribution
-
Expressed by cortical thymocytes, monocytes, macrophages, dendritic cells, B cells (highly expressed on marginal zone B cells in particular), and in some non-lymphoid cells
- Function
- Present lipid antigens to iNKT cells
- Ligand/Receptor
- When loaded with a lipid, is recognized by the Vα14i TCR from iNKT cells
- Cell Type
- B cells, Dendritic cells, Macrophages, Monocytes, Thymocytes
- Biology Area
- Immunology, Innate Immunity
- Molecular Family
- CD Molecules, MHC Antigens, TCRs
- Antigen References
-
1. Koch M, et al. 2005. Nat. Immunol. 6:819.
2. Liu X, et al. 2010. P. Natl. Acad. Sci. USA 107:13010.
3. Zeissig S, et al. 2010. J. Clin. Invest. 120:2889.
4. Teige A, et al. 2010. J. Immunol. 185:345.
- Gene ID
- 912 View all products for this Gene ID
- UniProt
- View information about CD1d on UniProt.org
