Purified anti-human CD307e (FcRL5) Antibody
- 产品名称:
- Purified anti-human CD307e (FcRL5) Antibody
- 产品类别:
- 抗体
- 产品编号:
- 340302
- 产品应用:
- 340302
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- P815 cells transfected with FcRL5
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
FC - Quality tested
IP - Reported in the literature, not verified in house
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.125 ?g per million cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.
- Application Notes
Additional reported applications (for the relevant formats) include: immunoprecipitation and blocking1. mAb 509f6 is able to block the binding of FcRL5 to all aggregated IgG isotypes.1
- Application References
(PubMed link indicates BioLegend citation) -
- Wilson TJ, et al. 2012. J. Immunol. 188:4741. (Block)
- Product Citations
-
- Obeng-Adjei N, et al. 2017. PLoS Pathog. 13:e1006576. PubMed
- RRID
- AB_2104586 (BioLegend Cat. No. 340302)
- Structure
- 106 kD, Fc receptor like, type 1 transmembrane protein, 6-8 Ig like C2 domains, 2 cytoplasmic ITIM motifs.
- Distribution
-
Germinal center B cells, tonsillar plasma cells.
- Ligand/Receptor
- Aggregated IgG
- Cell Type
- B cells, Plasma cells
- Biology Area
- Immunology
- Molecular Family
- CD Molecules
- Antigen References
-
1. Davis R, et al. 2007. Annu. Rev. Immunol. 207:528.
2. Mohan J, et al. 2006. Blood 107:4433.
3. Ise T, et al. 2007. Leukemia. 21:169.
- Gene ID
- 83416 View all products for this Gene ID
- UniProt
- View information about CD307e on UniProt.org