APC anti-human CD151 (PETA-3) Antibody -上海雅吉生物科技有限公司

规格	价格	库存
25tests	￥ 1704	1

Product Details

Verified Reactivity

Human

Antibody Type

Monoclonal

Host Species

Mouse

Immunogen

Human epidermoid carcinoma cell line HEp-3

Formulation

Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)

Preparation

The antibody was purified by affinity chromatography and conjugated with APC under optimal conditions.

Concentration

Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)

Storage & Handling

The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.

Application

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 ?l per million cells in 100 ?l staining volume or 5 ?l per 100 ?l of whole blood.

Excitation Laser

Red Laser (633 nm)

Application Notes

Additional reported applications (for the relevant formats) include: in vivo inhibition of metastasis of HEp-3 cells¹, Western blotting¹, immunocytochemical staining of HEp-3 cells¹, and CD151-transfected COS cells fixed with 0.25% glutaraldehyde.

Application References (PubMed link indicates BioLegend citation)

Testa JE, et al. 1999. Cancer Res. 59:3812. (Block, ICC, WB)

Product Citations

Yunusova NV, et al. 2021. Asian Pac J Cancer Prev. 22:861. PubMed

RRID

AB_10661726 (BioLegend Cat. No. 350405) AB_10661727 (BioLegend Cat. No. 350406)

Antigen Details

Structure: Member of the tetraspanin family (TM4SF), 29 kD protein, consist of two extracellular loop, four transmembrane domains and two cytoplasmic tails
Distribution: Immature hematopoietic cells, megakaryocytes, platelets, keratinocytes, epithelial cells, muscle cells, Schwann cells, vascular endothelium
Function: Cell adhesion, migration
Interaction: CD9, CD181, integrins α3β1, α5β1 and α6β4
Cell Type: Epithelial cells, Hematopoietic stem and progenitors, Megakaryocytes, Mesenchymal Stem Cells, Platelets
Biology Area: Angiogenesis, Cell Adhesion, Cell Biology, Cell Motility/Cytoskeleton/Structure, Immunology, Stem Cells
Molecular Family: Adhesion Molecules, CD Molecules
Antigen References: 1. Z?ller M. 2009. Nat. Rev. Cancer 9:40.
2. Ya?ez-Mó M, et al. 2008. Blood 112:3217.
3. Nishiuchi R, et al. 2005. Proc. Natl. Acad. Sci. USA 102:1939.
Gene ID: 977 View all products for this Gene ID
UniProt: View information about CD151 on UniProt.org

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