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Purified anti-human CD143 (Angiotensin-converting
产品名称:
Purified anti-human CD143 (Angiotensin-converting
产品类别:
抗体
产品编号:
344202
产品应用:
344202
[价格]
规格 价格 库存
100µg ¥ 1692 1

产品详情

Product Details

Verified Reactivity
Human
Antibody Type
Monoclonal
Host Species
Mouse
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography.
Concentration
0.5 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C.
Application

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.5 ?g per million cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.

RRID
AB_2222983 (BioLegend Cat. No. 344202)

Antigen Details

Structure
Single chain, type I transmembranal zinc metallopeptidase, 170 kD.
Distribution

Endothelial cells, some types of epithelial cells, activated macrophages and histiocytes.

Function
Regulates blood pressure by promoting vasoconstriction by the conversion of angiotensin I to angiotensin II and by the degradation of bradykinin, a vasodilator.
Ligand/Receptor
Angiotensin I, bradykinin.
Bioactivity
Blood pressure regulator.
Cell Type
Endothelial cells, Epithelial cells, Macrophages
Biology Area
Immunology
Molecular Family
CD Molecules
Antigen References

1. Nakamura T, et al. 2009. Int Heart J. 50:501.
2. Jayasooriya AP, et al. 2008. P. Natl. Acad. Sci. USA 105:6531.
3. Jokubaitis VJ, et al. 2008. Blood 111:4055.
4. Arndt PG, et al. 2006. J. Immunol. 177:7233.
5. Balyasnikova IV, et al. 2002. Biochem J. 362:585.

Gene ID
1636 View all products for this Gene ID
UniProt
View information about CD143 on UniProt.org

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