Purified anti-human CD143 (Angiotensin-converting
- 产品名称:
- Purified anti-human CD143 (Angiotensin-converting
- 产品类别:
- 抗体
- 产品编号:
- 344202
- 产品应用:
- 344202
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.5 ?g per million cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.
- RRID
- AB_2222983 (BioLegend Cat. No. 344202)
- Structure
- Single chain, type I transmembranal zinc metallopeptidase, 170 kD.
- Distribution
-
Endothelial cells, some types of epithelial cells, activated macrophages and histiocytes.
- Function
- Regulates blood pressure by promoting vasoconstriction by the conversion of angiotensin I to angiotensin II and by the degradation of bradykinin, a vasodilator.
- Ligand/Receptor
- Angiotensin I, bradykinin.
- Bioactivity
- Blood pressure regulator.
- Cell Type
- Endothelial cells, Epithelial cells, Macrophages
- Biology Area
- Immunology
- Molecular Family
- CD Molecules
- Antigen References
-
1. Nakamura T, et al. 2009. Int Heart J. 50:501.
2. Jayasooriya AP, et al. 2008. P. Natl. Acad. Sci. USA 105:6531.
3. Jokubaitis VJ, et al. 2008. Blood 111:4055.
4. Arndt PG, et al. 2006. J. Immunol. 177:7233.
5. Balyasnikova IV, et al. 2002. Biochem J. 362:585.
- Gene ID
- 1636 View all products for this Gene ID
- UniProt
- View information about CD143 on UniProt.org