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FITC anti-human CD36 Antibody
产品名称:
FITC anti-human CD36 Antibody
产品类别:
抗体
产品编号:
336203
产品应用:
336203
[价格]
规格 价格 库存
25tests ¥ 1212 1

产品详情

Product Details

Verified Reactivity
Human
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
Human platelets
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
Preparation
The antibody was purified by affinity chromatography, and conjugated with FITC under optimal conditions.
Concentration
Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 ?l per million cells in 100 ?l staining volume or 5 ?l per 100 ?l of whole blood.

Excitation Laser
Blue Laser (488 nm)
Application Notes

Additional reported applications (for the relevant formats) include: immunofluorescence2.

Application References

(PubMed link indicates BioLegend citation)
  1. Stelner E, et al. 2006. J. Cell Sci. 119:459.
  2. Stewart DA, et al. 2012. Mol. Cancer Res. 10:727. (IF)
Product Citations
  1. Miggitsch C, et al. 2019. EBioMedicine. 46:387. PubMed
  2. Caielli S, et al. 2021. Cell. 184(17):4464-4479.e19. PubMed
  3. Miao L, et al. 2021. Clin Transl Med. 11:e395. PubMed
  4. CL C, et al. 2012. PLoS One. 7:e38523. PubMed
  5. Genoula M, et al. 2018. Front Immunol. 9:459. PubMed
  6. Aoki T, et al. 2022. Ann Surg Oncol. :. PubMed
  7. Cillo AR, et al. 2021. Cell Rep Med. 2:100476. PubMed
  8. Ford BD, et al. 2021. Int J Mol Sci. 22:. PubMed
  9. Phansalkar R, et al. 2021. Elife. 10:. PubMed
  10. Martins AJ, et al. 2017. Cell Systems. 4(4):379-392.e12. PubMed
RRID
AB_1575029 (BioLegend Cat. No. 336203) AB_1575025 (BioLegend Cat. No. 336204)

Antigen Details

Structure
Integral membrane protein, CD36 family, single chain glycoprotein, 85-113 kD
Distribution

Expressed in various epithelial and endothelial cells, erythrocytes, platelets, monocytes/ macrophages, some macrophage-derived dendritic cells

Function
Scavenger receptor for thrombospondin, long chain fatty acids, anionic phospholipids, oxidized LDL, collagen types I, IV and V. Involved in recognition and phagocytosis of apoptotic cells, cell adhesion.
Ligand/Receptor
Thrombospondin, anionic phospholipids, oxidized LDL, collage types I, IV, and V
Cell Type
Dendritic cells, Endothelial cells, Epithelial cells, Erythrocytes, Macrophages, Monocytes, Platelets
Biology Area
Cell Biology, Immunology, Innate Immunity, Neuroinflammation, Neuroscience
Molecular Family
CD Molecules
Antigen References

1. Hogg N, et al. 1984. Immunology 53-753.
2. Greenwalt DE, et al. 1992. Blood 80:1105.
3. Armsesilla AL, et al.1994. J. Biol. Chem. 269:18985.
4. Endemann G, et al. 1993. J. Biol. Chem. 268:11811.

Gene ID
948 View all products for this Gene ID
UniProt
View information about CD36 on UniProt.org

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