Purified anti-p97/VCP Antibody
- 产品名称：
- Purified anti-p97/VCP Antibody
- 产品类别：
- 抗体
- 产品编号：
- 636801
- 产品应用：
- 636801
- Verified Reactivity
- Human, Mouse
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- Recombinant human valosin containing protein
- Formulation
- This antibody is provided in phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide at 0.5 mg/ml.
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/mL
- Storage & Handling
- Upon receipt, store?undiluted between 2°C and 8°C."
- Application
-
WB - Quality tested
IP, ICC?- Reported by the developer, not verified in house
- Recommended Usage
Each lot of this antibody is quality control tested by Western blotting. For Western blotting, suggested working dilution(s): Use 5 ?g per 5 mL?antibody dilution buffer for each mini-gel. For immunofluorescence microscopy: Use a dilution range of 1~4 ?g/mL. It is recommended that the reagent be titrated for optimal performance for each application.
- Application References
(PubMed link indicates BioLegend citation) -
- Shchedrina VA, et al. 2011. J Biol Chem. 186:42937. PubMed.
- Yi L, et al. 2012. Hum Mol Genet. 21:1794. PubMed.
- Yahiro K, et al. 2012. Infect Immun. 80:1803. PubMed.
- Product Citations
-
- Yi L, et al. 2012. Hum Mol Genet. 2.120833333. PubMed
- Yahiro K, et al. 2012. Infect Immun. 80:1803. PubMed
- Efimova I, et al. 2021. Front Immunol. 12:643144. PubMed
- Shchedrina V, et al. 2011. J Biol Chem. 286:42937. PubMed
- RRID
- AB_2257136 (BioLegend Cat. No. 636801) AB_2214641 (BioLegend Cat. No. 636802)
- Structure
- Belongs to the AAA ATPase family, homohexamer, forms a ring-shaped particle of 12.5 nm diameter and displays 6-fold radial symmetry.
- Interaction
- VCIP135, SELS/VIMP, SYVN1, DERL1, DERL2, DERL3, SVIP
- Bioactivity
- VCP is associated with a variety of cellular activities, including cell cycle control, membrane fusion after mitosis, regulates spindle disassembly at the end of mitosis, nuclear trafficking and the ubiquitin-proteasome degradation pathway.
- Biology Area
- Cell Biology, Cell Cycle/DNA Replication, Neuroscience, Neuroscience Cell Markers
- Molecular Family
- Endoplasmic Reticulum Markers
- Antigen References
-
1. Ye Y, et al. 2001. Nature 414:652.
- Gene ID
- 7415 View all products for this Gene ID
- UniProt
- View information about p97/VCP on UniProt.org
