Purified anti-human CD19 Antibody
- 产品名称：
- Purified anti-human CD19 Antibody
- 产品类别：
- 抗体
- 产品编号：
- 392502
- 产品应用：
- 392502
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- Human Chronic Lymphocytic Leukemia (CLL) cells
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
FC -?Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0??g per million cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.
- Application Notes
Clone 4G7 partially blocks anti-human CD19 clones HIB19 and SJ25C1 staining based on in-house testing
- Application References
(PubMed link indicates BioLegend citation) -
- Cabezudo E,?et al.?1999.?Haematologica.?84:413-8
- Van Zelm MC?et al.?2010.?J Clin Invest.?120:1265-74
- Product Citations
-
- Gehlert CL, et al. 2022. Front Immunol. 13:957874. PubMed
- Nugent JL, et al. 2021. iScience. 24:103421. PubMed
- Winterberg D, et al. 2021. J Clin Med. 10:. PubMed
- RRID
- AB_2721738 (BioLegend Cat. No. 392502)
- Structure
- Ig superfamily, type I transmembrane glycoprotein, 95 kD
- Distribution
-
Normal and malignant B lymphocytes
- Function
- B cell activation and differentiation
- Ligand/Receptor
- Forms complex with CD21 (CR2) and CD81 (TAPA-1), BCR coreceptor
- Cell Type
- B cells, Lymphocytes
- Biology Area
- Costimulatory Molecules, Immunology
- Molecular Family
- CD Molecules
- Antigen References
-
- Tedder T,?et al. 1994.?Immunol. Today 15:437.
- Bradbury L,?et al. 1993.?J. Immunol. 151:2915.
- Gene ID
- 930 View all products for this Gene ID
- UniProt
- View information about CD19 on UniProt.org
