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Purified anti-mouse CD319 Antibody
产品名称:
Purified anti-mouse CD319 Antibody
产品类别:
抗体
产品编号:
152002
产品应用:
152002
[价格]
规格 价格 库存
100µg ¥ 3456 1

产品详情

Product Details

Verified Reactivity
Mouse
Antibody Type
Monoclonal
Host Species
Rat
Immunogen
CD319-Fc fusion protein
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography.
Concentration
0.5 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C.
Application

FC - Quality tested
Direct ELISA, WB - Reported in the literature, not verified in house

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.25 ?g per million cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.

RRID
AB_2616915 (BioLegend Cat. No. 152002)

Antigen Details

Structure
Extracellular domain with one Ig like V-set domain and one Ig like C2-set domain, and an cytoplasmic domain with two immunoreceptor tyrosine-based switch motifs ITSMs.
Distribution

Spleen, lymph node, bone marrow, testis, thymus; NK cells, B cells, and subsets of T cells.

Function
Activates immune responses in NK cells when coupled with SAP-family adaptors (SAP, EAT-2, ERT).
Interaction
Interacts (via ITSM phosphorylated on Tyr-302) with SH2D1B, PTPN6/SHP-1, PTPN11/SHP-2, INPP5D/SHIP1, CSK and FYN, and SAP-family adaptors (SAP, EAT-2, ERT).
Cell Type
B cells, NK cells, T cells
Biology Area
Immunology
Molecular Family
CD Molecules
Antigen References

1. Li Y, et al. 2013. PLoS One 8(9):e76681.
2. Dongre P, et al. 2013. Mol. Immunol. 54:254-63.
3. Tovar V, et al. 2002. Immunogenetics 54:394.
4. Dong Z, et al. 2009. Nat. Immunol. 10:973.

Gene ID
75345 View all products for this Gene ID
UniProt
View information about CD319 on UniProt.org

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