Purified anti-RORγ Antibody
- 产品名称：
- Purified anti-RORγ Antibody
- 产品类别：
- 抗体
- 产品编号：
- 644902
- 产品应用：
- 644902
- Verified Reactivity
- Human
- Reported Reactivity
- Mouse
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- Human RORγ-GST recombinant protein
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
WB - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by Western blotting. Western blotting, suggested working dilution: 1 to 4 ?g/ml. It is recommended that the reagent be titrated for optimal performance for each application.
- Application Notes
This product weakly reacts with Mouse.
- Application References
(PubMed link indicates BioLegend citation) -
- Klemann C, et al. 2009. Am J Pathol. 174:2234. PubMed
- Product Citations
-
- Klemann C, et al. 2009. Am J Pathol. 174:2234. PubMed
- RRID
- AB_1595502 (BioLegend Cat. No. 644902)
- Structure
- Belongs to the nuclear hormone receptor family, NR1 subfamily. Contains 1 nuclear receptor DNA-binding domain. RORγ has two isoforms: γ1 and γ2 (also referred to as RORγt). The RORγt differs from the RORγ1 isoform in th
- Distribution
-
Th17 cells
- Function
- RORγt is essential for lymph nodes and Peyer's patches development. RORγt plays a critical role in control apoptosis during thymopoiesis and T cell homeostasis.
- Cell Type
- Th17
- Biology Area
- Cell Biology, Immunology
- Molecular Family
- Nuclear Markers
- Antigen References
-
1. Medvedev A, et al. 1997. Genomics 46:93.
2. He YW, et al. 1998. Immunity 9:797.
3. Eberl G, et al. 2004. Nat. Immunol. 5:64.
- Gene ID
- 19885 View all products for this Gene ID
- UniProt
- View information about RORg on UniProt.org
