Purified anti-Cortactin (CTTN) Antibody
- 产品名称：
- Purified anti-Cortactin (CTTN) Antibody
- 产品类别：
- 抗体
- 产品编号：
- 868101
- 产品应用：
- 868101
- Verified Reactivity
- Human, Mouse, Rat
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
WB - Quality tested
ICC - Verified
- Recommended Usage
Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested use of this reagent is 0.5 - 10 ?g per ml. For immunocytochemistry, a concentration range of 2 - 10 μg/ml is recommended. It is recommended that the reagent be titrated for optimal performance for each application.
- RRID
- AB_2810811 (BioLegend Cat. No. 868101) AB_2810812 (BioLegend Cat. No. 868102)
- Structure
- Cortactin is a 634 amino acid protein with predicted molecular mass of ~ 71 kD and observed molecular mass of ~ 80 kD.
- Distribution
-
Tissue Distribution: Ubiquitously expressed
Cellular Distribution: Plasma membrane, cytoskeleton, cytosol, and Golgi apparatus
- Function
- Cortactin promotes polymerization and the rearrangement of the actin cytoskeleton upon external stimulations.
- Interaction
- SHANK2, SHANK3, FGD1, ABL2, KCNA2, PLXDC2, SRCIN1, SMASN1, ASAP1.
- Cell Type
- Astrocytes, Endothelial cells, Neurons, Oligodendrocytes
- Biology Area
- Cancer Biomarkers, Cell Motility/Cytoskeleton/Structure, Neurodegeneration, Neuroscience, Protein Trafficking and Clearance, Synaptic Biology
- Molecular Family
- Cytoskeletal Proteins, Synaptic Vesicle Trafficking/Endocytosis
- Antigen References
-
- Ramos-Garcia P, et al. 2019. Oral Dis. 25(4):949
- Schnoor M, et al. 2018. Trends Cell Biol. 28(2):79
- Yin M, et al. 2017. Oncotarget. 8(50):88232
- Gene ID
- 2017 View all products for this Gene ID 13043 View all products for this Gene ID 60465 View all products for this Gene ID
- UniProt
- View information about Cortactin on UniProt.org
