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APC anti-Syk Antibody
产品名称:
APC anti-Syk Antibody
产品类别:
抗体
产品编号:
644305
产品应用:
644305
[价格]
规格 价格 库存
25tests ¥ 1644 1

产品详情

Product Details

Verified Reactivity
Human
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
Human Syk peptide aa314-339
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
Preparation
The antibody was purified by affinity chromatography and conjugated with APC under optimal conditions.
Concentration
Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

ICFC -?Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by intracellular immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 ?l per million cells in 100 ?l staining volume or 5 ?l per 100 ?l of whole blood.

Excitation Laser
Red Laser (633 nm)
Application Notes

This product is for in vitro research use only. It is not to be used for commercial purposes. Use of this product to produce products for sale or for diagnostic therapeutic or drug discovery purposes is prohibited. In order to obtain a license to use this product for commercial purposes, contact The Regents of the University of California.

Application References

(PubMed link indicates BioLegend citation)
  1. Van Oers, et al. 1995. J. Exp. Med. 182:1585
  2. Chu DH, et al. 1999. J. Immunol. 163:2610.
Product Citations
  1. He X, et al. 2018. EMBO J. 37:e97980. PubMed
  2. Shemesh A, et al. 2022. J Exp Med. 219:. PubMed
RRID
AB_2687145 (BioLegend Cat. No. 644305) AB_2687146 (BioLegend Cat. No. 644306)

Antigen Details

Structure
Non-receptor associated tyrosine kinase, contains 2 SH2 domains, 72 kD
Distribution

Cytoplasmic protein, widely expressed in hematopoietic cells

Function
Couples immunoreceptor to downstream signaling events that mediate cellular responses including proliferation, differentiation, and phagocytosis
Biology Area
Cell Biology, Immunology, Signal Transduction
Antigen References

1. Taniguchi T,?et al.?1991.?J. Biol. Chem.?266:15790.
2. Toyabe SL,?et al.?2001.Immunology?103:164.

Gene ID
6850 View all products for this Gene ID
UniProt
View information about Syk on UniProt.org

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