Purified anti-mouse/human CD207 (Langerin) Antibo
- 产品名称：
- Purified anti-mouse/human CD207 (Langerin) Antibo
- 产品类别：
- 抗体
- 产品编号：
- 144201
- 产品应用：
- 144201
- Verified Reactivity
- Mouse, Human
- Reported Reactivity
- Cynomolgus, Rabbit, Pig
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- Langerin extracellular domain-Fc fusion protein
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤1.0 ?g per million cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.
- Product Citations
-
- Park S, et al. 2021. Nat Cell Biol. 23:476. PubMed
- Kubick BJ, et al. 2020. J Invest Dermatol. 140:891. PubMed
- RRID
- AB_2562087 (BioLegend Cat. No. 144201) AB_2562088 (BioLegend Cat. No. 144202)
- Structure
- Single-pass type II transmembrane protein, 40 kD, one C-type lectin domain, homotrimer
- Distribution
-
Langerhans cells, subsets of thymic and splenic dendritic cells
- Function
- Antigen uptake, antigen processing
- Ligand/Receptor
- Mannose, n-acetylglucosamine, fucose, sulfated glycans
- Cell Type
- Dendritic cells, Langerhans cells
- Biology Area
- Immunology, Innate Immunity
- Molecular Family
- CD Molecules
- Antigen References
-
1. Romani N, et al. 2012. Curr. Top. Microbiol. Immunol. 351:113.
2. Kaplan DH. 2010. Trends Immunol. 31:446.
3. Clausen BE and Kel JM. 2010. Immunol. Cell. Biol. 88:351.
4. Merad M, et al. 2008. Nat. Rev. Immunol. 8:935.
- Gene ID
- 246278 View all products for this Gene ID 50489 View all products for this Gene ID
- UniProt
- View information about CD207 on UniProt.org
