APC anti-mouse/human CD207 (Langerin) Antibody
- 产品名称：
- APC anti-mouse/human CD207 (Langerin) Antibody
- 产品类别：
- 抗体
- 产品编号：
- 144205
- 产品应用：
- 144205
- Verified Reactivity
- Mouse, Human
- Reported Reactivity
- Cynomolgus, Rabbit, Pig
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- Langerin extracellular domain-Fc fusion protein
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography and conjugated with APC under optimal conditions.
- Concentration
- 0.2 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.25 ?g per million cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.
- Excitation Laser
- Red Laser (633 nm)
- Product Citations
-
- Wong E, et al. 2019. Cell Rep. 29:3047. PubMed
- Samarchith P Kurup et al. 2019. Cell host & microbe. 25(4):565-577 . PubMed
- Hartwig T et al. 2018. Cell reports. 25(13):3564-3572 . PubMed
- Wuggenig P, et al. 2020. Commun Biol. 3:130. PubMed
- Stotesbury C, et al. 2020. Aging Cell. 19:e13170. PubMed
- Tran S, et al. 2020. Immunity. 53(3):627-640.e5. PubMed
- RRID
- AB_2561997 (BioLegend Cat. No. 144205) AB_2561998 (BioLegend Cat. No. 144206)
- Structure
- Single-pass type II transmembrane protein, 40 kD, one C-type lectin domain, homotrimer
- Distribution
-
Langerhans cells, subsets of thymic and splenic dendritic cells
- Function
- Antigen uptake, antigen processing
- Ligand/Receptor
- Mannose, n-acetylglucosamine, fucose, sulfated glycans
- Cell Type
- Dendritic cells, Langerhans cells
- Biology Area
- Immunology, Innate Immunity
- Molecular Family
- CD Molecules
- Antigen References
-
1. Romani N, et al. 2012. Curr. Top. Microbiol. Immunol. 351:113.
2. Kaplan DH. 2010. Trends Immunol. 31:446.
3. Clausen BE and Kel JM. 2010. Immunol. Cell. Biol. 88:351.
4. Merad M, et al. 2008. Nat. Rev. Immunol. 8:935.
- Gene ID
- 246278 View all products for this Gene ID 50489 View all products for this Gene ID
- UniProt
- View information about CD207 on UniProt.org
