PE anti-mouse PDC-TREM Antibody
- 产品名称：
- PE anti-mouse PDC-TREM Antibody
- 产品类别：
- 抗体
- 产品编号：
- 139203
- 产品应用：
- 139203
- Verified Reactivity
- Mouse
- Antibody Type
- Monoclonal
- Host Species
- Rat
- Immunogen
- Recombinant soluble PDC-TREM
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions.
- Concentration
- 0.2 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤1.0 ?g per million cells in 100 ?l volume.? It is recommended that the reagent be titrated for optimal performance for each application.
- Excitation Laser
- Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
- Application Notes
Additional reported applications (for the relevant formats) include: Western blot1.
- Application References
(PubMed link indicates BioLegend citation) -
- Watarai H, et al. 2008. Proc. Natl. Acad. Sci. USA 105:2993. (WB)
- Rahim MM, et al. 2013. J. Immunol. 190:3994. PubMed.
- Product Citations
-
- Jtte BB, et al. 2021. iScience. 24(8):102833. PubMed
- Naing A et al. 2019. Cell reports. 26(5):1242-1257 . PubMed
- Rahim M, et al. 2013. J Immunol. 190:3994. PubMed
- RRID
- AB_10613646 (BioLegend Cat. No. 139203) AB_10613471 (BioLegend Cat. No. 139204)
- Structure
- Member of the TREM receptor family. Type I protein composed of an extracellular region with a single V-type Ig domain, a transmembrane domain with a lysine residue and a cytoplasmic domain with no recognized signaling motifs.
- Distribution
- Expressed on TLR activated plasmacytoid dendritic cells (PDC)
- Function
- Signal transduction, induces the production of IFN-α
- Interaction
- DAP12, Plexin-A1, PI3K, Erk 1/2
- Cell Type
- Dendritic cells
- Biology Area
- Cell Biology, Immunology, Innate Immunity, Signal Transduction
- Molecular Family
- Protein Kinases/Phosphatase
- Antigen References
-
1. Jill W, et al. 2009. Curr. Opin. Immunol. 21:38.
2. Lanier LL. 2009. Immunol. Rev. 227:150.
- Gene ID
- 328830 View all products for this Gene ID
- UniProt
- View information about PDC-TREM on UniProt.org
