Ultra-LEAF™ Purified anti-mouse CD226 (DNAM-
- 产品名称：
- Ultra-LEAF™ Purified anti-mouse CD226 (DNAM-
- 产品类别：
- 抗体
- 产品编号：
- 132009
- 产品应用：
- 132009
- Verified Reactivity
- Mouse
- Antibody Type
- Monoclonal
- Host Species
- Rat
- Immunogen
- Jurkat cells transfected with mouse CD226
- Formulation
- 0.2 ?m filtered in phosphate-buffered solution, pH 7.2, containing no preservative. Endotoxin level is < 0.01 EU/?g of the protein (< 0.001 ng/?g of the protein) as determined by the LAL test.
- Preparation
- The Ultra-LEAF? (Low Endotoxin, Azide-Free) antibody was purified by affinity chromatography.
- Concentration
- The antibody is bottled at the concentration indicated on the vial, typically between 2 mg/mL and 3 mg/mL. Older lots may have also been bottled at 1 mg/mL. To obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C. This Ultra-LEAF? solution contains no preservative; handle under aseptic conditions.
- Application
-
FC -?Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.25??g per million cells in 100 ?L volume. It is recommended that the reagent be titrated for optimal performance for each application.
- Application References
(PubMed link indicates BioLegend citation) -
- Dardalhon V, et al. 2005. J. Immunol. 175:1558
- RRID
- AB_2876467 (BioLegend Cat. No. 132009) AB_2876467 (BioLegend Cat. No. 132010)
- Structure
- 65 kd glycoprotein of a member of Ig-superfamily containing 2 immunologlobulin-like domains.
- Distribution
-
Expressed on majority of CD8+ and CD4+ T cells, NK cells, monocytes/macrophages and a subset of B cells. Reported to upregulated on Th1 cells, but downregulated in Th2 cells.
- Function
- Mediates cellular adhesion, involved in LFA-1 co-stimulatory signal for T cell differentiation and proliferation
- Ligand/Receptor
- CD112 and CD155
- Cell Type
- B cells, Macrophages, Monocytes, NK cells, T cells, Th1
- Biology Area
- Immunology
- Molecular Family
- Adhesion Molecules, CD Molecules
- Antigen References
-
1. Tahara Hanaoka S et al. 2006 Blood 107:1491
2. Shibuya K et al. 2003. J. Exp. Med. 198:1829
- Gene ID
- 225825 View all products for this Gene ID
- UniProt
- View information about CD226 on UniProt.org
