PE anti-mouse Granzyme A Antibody
- 产品名称：
- PE anti-mouse Granzyme A Antibody
- 产品类别：
- 抗体
- 产品编号：
- 149703
- 产品应用：
- 149703
- Verified Reactivity
- Mouse
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- Full length recombinant granzyme A of mouse origin.
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions.
- Concentration
- 0.2 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
ICFC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by intracellular immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.25 ?g per million cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.
- Excitation Laser
- Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
- Application References
(PubMed link indicates BioLegend citation) -
- Fehniger TA, et al. 2007. Immunity 26:798. (ICFC)
- Product Citations
-
- Santiago L, et al. 2020. Cell Rep. 107847:32. PubMed
- Findlay EG, et al. 2019. Oncoimmunology. 8:1608106. PubMed
- Wu J, et al. 2020. Sci Adv. 6:eaba3458. PubMed
- Jiang P, et al. 2021. Nat Methods. 18:1181. PubMed
- Uchil PD et al. 2018. Cell host & microbe. 25(1):87-100 . PubMed
- Wiedemann GM, et al. 2020. Cell Rep. 33:108498. PubMed
- Souza COS, et al. 2021. iScience. 24(6):102548. PubMed
- Thom SR, et al. 2017. J Appl Physiol (1985). 123:297. PubMed
- RRID
- AB_2565309 (BioLegend Cat. No. 149703) AB_2565310 (BioLegend Cat. No. 149704)
- Structure
- 29 kD, Homodimer, Serine protease
- Distribution
-
Cytotoxic T cells and natural killer cells (NK); low on granulocytes, B cells, and activated dendritic cells (DCs).
- Function
- Induction of cell death and apoptosis.
- Cell Type
- T cells, NK cells
- Biology Area
- Cell Biology, Immunology, Innate Immunity, Neuroscience
- Molecular Family
- Proteases, Enzymes and Regulators
- Antigen References
-
1. Susanto O, et al. 2013. Cell Death Differ. 20:1183.
2. Ebnet K, et al. 1995. EMBO J. 14:4230.
3. Jenne DE, et al. 1988. Immunol. Rev. 103:53.
- Gene ID
- 14938 View all products for this Gene ID
- UniProt
- View information about Granzyme A on UniProt.org
