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PE anti-human CD290 (TLR10) Antibody
产品名称:
PE anti-human CD290 (TLR10) Antibody
产品类别:
抗体
产品编号:
354603
产品应用:
354603
[价格]
规格 价格 库存
25tests ¥ 1836 1

产品详情

Product Details

Verified Reactivity
Human
Reported Reactivity
Baboon
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
Purified extracellular domain of human TLR10 (amino acids 20-474) (NP_001017388 )
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
Preparation
The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions.
Concentration
Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 ?l per million cells in 100 ?l staining volume or 5 ?l per 100 ?l of whole blood.

Excitation Laser
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
Application Notes

View more applications data for this product in our Scientific Poster Library.

Application References

(PubMed link indicates BioLegend citation)
  1. Guan Y, et al. 2010. J. Immunol. 184:5094.
RRID
AB_11219598 (BioLegend Cat. No. 354603) AB_11219791 (BioLegend Cat. No. 354604)

Antigen Details

Structure
Member of the toll-like receptor family, type I membrane protein, 91-100 kD
Distribution

B cells, Treg cells, plasmacytoid DCs

Function
Interacts with MyD88 and TRAF6, which results in NF-kB activation and cytokine secretion
Ligand/Receptor
MyD88 and TRAF6
Cell Type
B cells, Dendritic cells, Tregs
Biology Area
Immunology, Innate Immunity
Molecular Family
CD Molecules, Toll Like Receptors
Antigen References

1. Chuang T, et al. 2001. Biochim. Biophys. Acta. 1518:157.
2. Hornung V, et al. 2002. J. Immunol. 168:4531.
3. Bourke E, et al. 2003. Blood 102:956.

Gene ID
81793 View all products for this Gene ID
UniProt
View information about CD290 on UniProt.org

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