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Purified anti-mouse CD365 (Tim-1) Antibody
产品名称:
Purified anti-mouse CD365 (Tim-1) Antibody
产品类别:
抗体
产品编号:
151702
产品应用:
151702
[价格]
规格 价格 库存
100µg ¥ 2532 1

产品详情

Product Details

Verified Reactivity
Mouse
Antibody Type
Monoclonal
Host Species
Rat
Immunogen
Recombinant mouse TIM-1 (igV domain) FC chimera IFA
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography.
Concentration
0.5 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C.
Application

FC - Quality tested
Direct ELISA - Reported in the literature, not verified in house

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.75 ?g per million cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.

Product Citations
  1. Wagner AK, et al. 2017. Nat Commun. 8:15627. PubMed
RRID
AB_2616785 (BioLegend Cat. No. 151702)

Antigen Details

Structure
Transmembrane protein containing immunoglobulin domain and mucin-like domain with the predicted molecular weight of 33 kD.
Distribution

Developmentally regulated; highly expressed in embryonic development in blastocysts. Expressed on activated CD4+ lymphocytes, especially Th2 cell lines.

Function
Binds hepatitis virus, may play a critical role in immune responses and the development of atopic diseases (in particular airway hyperreactivity).
Ligand/Receptor
Binds hepatitis A virus in humans, Tim-4, and LMIR5/CD300b.
Biology Area
Cell Biology, Cell Proliferation and Viability, Immunology
Molecular Family
CD Molecules, TCRs
Antigen References

1. McIntire JJ, et al. 2001. Nat. Immunol. 2:1109.
2. Kuchroo VK, et al. 2003. Nat. Rev. Immunol. 3:454.
3. Wills-Karp M, et al. 2001. Nat. Rev. Immunol. 1:69.
4. Meyers JH, et al. 2005. Nat. Immunol. 6(5):455.
5. Umetsu S, et al. 2005. Nat. Immunol. 6:447.
6. Lee HH, et al. 2010. J. Immunol. 185:5225.

Gene ID
171283 View all products for this Gene ID
UniProt
View information about CD365 on UniProt.org

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