PE anti-human CD166 Antibody
- 产品名称：
- PE anti-human CD166 Antibody
- 产品类别：
- 抗体
- 产品编号：
- 343903
- 产品应用：
- 343903
[价格]
| 规格 |
价格 |
库存 |
| 25tests |
￥ 1680 |
1 |
- Verified Reactivity
- Human
- Reported Reactivity
- African Green, Baboon, Cynomolgus, Rhesus
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- Cultured human thymic epithelial cells
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
- Preparation
- The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions.
- Concentration
- Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 ?l per million cells in 100 ?l staining volume or 5 ?l per 100 ?l of whole blood.
- Excitation Laser
- Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
- Application Notes
Additional reported applications (for the relevant formats) include: immunohistochemical staining of paraffin-embedded tissue sections and immunofluorescence.1
- Application References
(PubMed link indicates BioLegend citation) -
- Pretzel D, et al. 2011. Arthritis Res. Ther. 13:R64. (IHC, IF, FC)
- Product Citations
-
- Weeks AM, et al. 2021. Proc Natl Acad Sci U S A. 118: . PubMed
- Fielding CA et al. 2017. eLife. 6 pii: e22206. PubMed
- Radhakrishnan S, et al. 2019. Mol Med Rep. 20:813. PubMed
- Slamecka J, et al. 2017. Cell Cycle. 17:330. PubMed
- Guney-Esken G, et al. 2021. Stem Cell Res Ther. 12:287. PubMed
- Tu S, et al. 2020. Cellular Signalling. 73:109695. PubMed
- Argüello RJ, et al. 2012. PLoS One. 7:e35966. PubMed
- Morton JJ, et al. 2018. Mol Carcinog. 57:1651. PubMed
- Liang C, et al. 2021. Cell Res. 31:187. PubMed
- Chulpanova DS, et al. 2020. Bioengineering (Basel). 7:00. PubMed
- Wu CL, et al. 2021. Nat Commun. 12:362. PubMed
- Aldeghaither DS, et al. 2019. Cancer Immunol Res. 7:230. PubMed
- Morton JJ, et al. 2020. Molecular Cancer Research. 19(2):346-357. PubMed
- Bi S, et al. 2020. Protein Cell. 0.79375. PubMed
- Alhaj Hussen K, et al. 2017. Immunity. 47:680. PubMed
- Yang C et al. 2019. Int J Mol Med. 43(3):1395-1405 . PubMed
- Houtsma R, et al. 2021. STAR Protoc. 2:100864. PubMed
- Ayhan S, et al. 2021. Journal of Cell Science. 134(6):. PubMed
- Chulpanova DS, et al. 2021. Biology (Basel). 10:. PubMed
- Xu L, et al. 2016. Cancer Res . 76(23):6901-6910. PubMed
- Guney-Esken G, et al. 2021. Methods Mol Biol. 2549:23. PubMed
- Duclos GE, et al. 2019. Sci Adv. 5:eaaw3413. PubMed
- Fernandez HR, et al. 2018. Cell Death Differ. 25:1239. PubMed
- Fu L, et al. 2019. PLoS Biol. 17:e3000201. PubMed
- Thiel A, et al. 2015. Sci Rep. 5: 17685. PubMed
- RRID
- AB_2289303 (BioLegend Cat. No. 343903) AB_2289302 (BioLegend Cat. No. 343904)
- Structure
- A type I transmembrane glycoprotein belonging to the Ig superfamily of proteins.
- Distribution
-
CD166 is expressed on activated T cells, activated monocytes, epithelial cells, fibroblasts, and neurons.
- Function
- Play an important role in mediating adhesion interactions between thymic epithelial cells and CD6+ cells during intrathymic T cell development.
- Ligand/Receptor
- CD6
- Cell Type
- Epithelial cells, Fibroblasts, Mesenchymal Stem Cells, Monocytes, Neurons, T cells
- Biology Area
- Immunology, Stem Cells
- Molecular Family
- Adhesion Molecules, CD Molecules
- Antigen References
-
1. Aruffo A, et al. 1997. Immunol Today. 18(10):498
2. Patel DD, et al. 1995. J. Exp. Med. 181:2213
3. Bowen MA, et al. 1995. J. Exp. Med. 181:1563
4. Horst D, et al. 2009. Cancer Invest. 22:1
- Gene ID
- 214 View all products for this Gene ID
- UniProt
- View information about CD166 on UniProt.org
