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首页 > 抗体蛋白 > 抗体
FITC anti-mouse I-A
产品名称：
FITC anti-mouse I-A
产品类别：
抗体
产品编号：
115005
产品应用：
115005
[价格]
规格 价格 库存
50µg ￥ 1128 1

产品详情

Product Details

Verified Reactivity
Mouse
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
(C3H x BALB/c)F1 mouse cells
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography, and conjugated with FITC under optimal conditions.
Concentration
0.5 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested
Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤1.0 ?g per million cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.

Excitation Laser
Blue Laser (488 nm)
Application Notes

Additional reported applications (for the relevant formats) include: immunofluorescence microscopy2, and immunohistochemical staining of acetone-fixed frozen sections.

Does not cross-react with other haplotypes (e.g., a, b, k, p, q, s).

Application References

(PubMed link indicates BioLegend citation)
  1. Hiramine C, et al. 1995. Cell. Immunol. 160:157.
  2. Wang Z, et al. 2004. J. Immunol. 172:5924.
  3. Ma XT, et al. 2006. Cancer Research 66:1169.
  4. Norian LA and Allen PM. 2004. J. Immunol. 173:835. PubMed
  5. Tian C, et al. 2007. J. Immunol. 179:6762.
Product Citations
  1. Ohashi K, et al. 2014. Mol Biol Cell. 25:828. PubMed
  2. Meng X, et al. 2017. PLoS One. 10.1371/journal.pone.0184781. PubMed
  3. Turner JA, et al. 2020. Immunity. 53:1202. PubMed
  4. Aldon Y, et al. 2020. J Immunol. 204:903. PubMed
  5. Kodumudi KN, et al. 2019. Front Immunol. 10:1939. PubMed
  6. Ma X, et al. 2006. Cancer Res. 66:1169. PubMed
  7. Harb H, et al. 2021. Immunity. 54(6):1186-1199.e7. PubMed
  8. Kumagai S, et al. 2020. Immunity. 53(1):187-203.e8. PubMed
  9. Wang Y, et al. 2020. Vaccines (Basel). 8:. PubMed
  10. Lisse TS, et al. 2020. NPJ Regen Med. 5:13. PubMed
  11. Rana MN, et al. 2021. Front Pharmacol. 12:643215. PubMed
  12. Gupta P, et al. 2016. PLoS One. 11: 0154725. PubMed
RRID
AB_313620 (BioLegend Cat. No. 115005) AB_313621 (BioLegend Cat. No. 115006)

Antigen Details

Structure
MHC class II
Distribution

B cell and activated T cells, APCs of H-2d?mice

Function
Antigen presentation
Ligand/Receptor
CD3/TCR, CD4
Cell Type
Antigen-presenting cells, B cells, T cells, Tregs
Biology Area
Immunology, Innate Immunity
Molecular Family
MHC Antigens
Antigen References

1. Watts C. 1997. Ann. Rev. Immunol. 15:821.
2. Pamer E, et al. 1998. Ann. Rev. Immunol. 16:323.
3. Wall KA, et al. 1983. J. Immunol. 131:1056.
4. Ridgway WM, et al. 1998. J. Exp. Med. 188:2267.

Gene ID
14961 View all products for this Gene ID
UniProt
View information about I-Ad on UniProt.org

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