PE anti-mouse Ly108 Antibody
- 产品名称：
- PE anti-mouse Ly108 Antibody
- 产品类别：
- 抗体
- 产品编号：
- 134605
- 产品应用：
- 134605
- Verified Reactivity
- Mouse
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- Thymocytes
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions.
- Concentration
- 0.2 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 ?g per 106 cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.
- Excitation Laser
- Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
- Application References
(PubMed link indicates BioLegend citation) -
- Fu GF, et al. 2012. Int Immunol. 24:197. PubMed.
- Product Citations
-
- Fitzgerald B, et al. 2021. Cell Rep Methods. 1:. PubMed
- Mitchell JE, et al. 2021. Cell Reports. 35(2):108966. PubMed
- Siddiqui I et al. 2019. Immunity. 50(1):195-211 . PubMed
- Chen Z et al. 2019. Immunity. 51(5):840-855 . PubMed
- De Ponte Conti B, et al. 2021. Elife. 10:. PubMed
- Beltra JC, et al. 2020. Immunity. 52(5):825-841. PubMed
- Blanchard L, et al. 2022. STAR Protoc. 3:101444. PubMed
- Chen Z, et al. 2021. Cell. 184(5):1262-1280.e22. PubMed
- Di Pilato M, et al. 2021. Cell. 184(17):4512-4530.e22. PubMed
- Fu G, et al. 2012. Int Immunol. 24:197. PubMed
- RRID
- AB_1659258 (BioLegend Cat. No. 134605) AB_2188095 (BioLegend Cat. No. 134606)
- Structure
- A glycoprotein of the signaling lymphocytic activation molecule family of cell surface receptor. It is a novel member of the CD2 subfamily of the Ig superfamily.
- Distribution
-
Expressed on T cells, B cells, macrophages, dendritic cells, NK cells, and granulocytes.
- Function
- Play an important role in CD4+ T cell responses, innate immunity to bacteria and parasites, and NK cell function.
- Ligand/Receptor
- Ly108
- Cell Type
- B cells, Dendritic cells, Granulocytes, Macrophages, NK cells, T cells
- Biology Area
- Immunology, Innate Immunity
- Antigen References
-
1. Howie D, et al. 2005. J. Immunology. 174 (10):5931
2 Kumar KR, et al. 2006. Science. 312(5780):1665
3. Zhong MC, et al. 2008. J. Biol. Chem. 283 (28):19255
4. Peck SR et al. 2000. Immunogenetics. 52:63
- Gene ID
- 30925 View all products for this Gene ID
- UniProt
- View information about Ly108 on UniProt.org
