PerCP/Cyanine5.5 anti-mouse CD40 Antibody
- 产品名称：
- PerCP/Cyanine5.5 anti-mouse CD40 Antibody
- 产品类别：
- 抗体
- 产品编号：
- 124623
- 产品应用：
- 124623
- Verified Reactivity
- Mouse
- Antibody Type
- Monoclonal
- Host Species
- Rat
- Immunogen
- Recombinant mouse CD40 protein
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography and conjugated with PerCP/Cyanine5.5 under optimal conditions.
- Concentration
- 0.2 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤1.0 ?g per million cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.
* PerCP/Cyanine5.5 has a maximum absorption of 482 nm and a maximum emission of 690 nm.
- Application Notes
For highly sensitive assays, we recommend Ultra-LEAF? purified antibody (Cat. No. 124627 &124628) with a low?endotoxin limit?(Endotoxin < 0.01 EU/?g).
- Additional Product Notes
- BioLegend is in the process of converting the name PerCP/Cy5.5 to PerCP/Cyanine5.5. The dye molecule remains the same, so you should expect the same quality and performance from our PerCP/Cyanine5.5 products. Contact Technical Service if you have any questions.
- Application References
(PubMed link indicates BioLegend citation) -
- Hasbold J, et al. 1994. Eur. J. Immunol. 24:1835.
- Bourgeois C, et al. 2002. Science 297:2060.
- Product Citations
-
- Gruber T, et al. 2020. JCI Insight. 5:00. PubMed
- Kremenovic M, et al. 2022. J Immunother Cancer. 10:. PubMed
- Francian A, et al. 2021. J Drug Target. 29:754. PubMed
- Samarchith P Kurup et al. 2019. Cell host & microbe. 25(4):565-577 . PubMed
- Ding X, et al. 2019. J Am Heart Assoc. 8:e011211. PubMed
- Lucas ED, et al. 2020. Cell Reports. 33(2):108258. PubMed
- Ravindran A, et al. 2014. Carcinogenesis. 35:959. PubMed
- Aglas L, et al. 2018. J Allergy Clin Immunol. 142:984. PubMed
- RRID
- AB_2561473 (BioLegend Cat. No. 124623) AB_2561474 (BioLegend Cat. No. 124624)
- Structure
- 48 kD type I transmembrane glycoprotein, a member of the tumor necrosis factor receptor (TNFR) superfamily.
- Distribution
-
Expressed on B lymphocytes and other antigen-presenting cells, such as macrophages, follicular dendritic cells, etc.
- Function
- Regulates B cell growth and differentiation and Ig isotype switching. Interaction of CD40 with its ligand, CD154, on activated T cells is important for immune response.
- Ligand/Receptor
- CD154 on T cells
- Cell Type
- Antigen-presenting cells, B cells, Dendritic cells, Macrophages
- Biology Area
- Cell Biology, Costimulatory Molecules, Immunology, Neuroscience, Neuroscience Cell Markers
- Molecular Family
- CD Molecules
- Antigen References
-
1. Grewal IS, et al. 1998. Annu Rev Immunol 16:111.
- Gene ID
- 21939 View all products for this Gene ID
- UniProt
- View information about CD40 on UniProt.org
