APC anti-rat CD161 Antibody
- 产品名称：
- APC anti-rat CD161 Antibody
- 产品类别：
- 抗体
- 产品编号：
- 205606
- 产品应用：
- 205606
- Verified Reactivity
- Rat
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- LEW rat splenic NK cells
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography and conjugated with APC under optimal conditions.
- Concentration
- 0.2 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.25 ?g per million cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.
- Excitation Laser
- Red Laser (633 nm)
- Application Notes
3.2.3 recognizes a common epitope of NKR-1P1a (CD161a) and NKR-P1b (CD161b).
- Application References
(PubMed link indicates BioLegend citation) -
- Chambers W, et al. 1989. J. Exp. Med. 169:1373. (FC)
- Product Citations
-
- Noto FK, et al. 2020. PLoS One. 15:e0240169. PubMed
- Chen C, et al. 2018. J Neuroinflammation. 15:167. PubMed
- Hall JM, et al. 2021. Infect Immun. 89:e0030421. PubMed
- Hall JM, et al. 2021. Infect Immun. 89:e0034621. PubMed
- Ruppert KA, et al. 2018. Sci Rep. 8:480. PubMed
- RRID
- AB_11142680 (BioLegend Cat. No. 205606)
- Structure
- Type II transmembrane C-type lectin, 30 kD.
- Distribution
-
NK cells, subset of T cells, dendritic cells, activated monocytes.
- Function
- NKR-P1a is a NK cell-activating receptor; NKR-P1b is a NK cell-inhibitory receptor.
- Ligand/Receptor
- LLT1-ligand lectin like transcript 1; KLR-killer cell lectin like receptor.
- Cell Type
- Dendritic cells, Monocytes, NK cells, T cells
- Biology Area
- Cell Biology, Immunology, Innate Immunity, Signal Transduction
- Molecular Family
- CD Molecules
- Antigen References
-
1. Chambers WH, et al. 1989. J. Exp. Med. 169:1373.
2. Brink M, et al. 1990. J. Exp. Med. 171:197.
3. Li J, et al. 2003. Int. Immunol. 15:411.
- Gene ID
- 362443 View all products for this Gene ID
- UniProt
- View information about CD161 on UniProt.org
