Purified anti-Gemin 2 Antibody
- 产品名称：
- Purified anti-Gemin 2 Antibody
- 产品类别：
- 抗体
- 产品编号：
- 862901
- 产品应用：
- 862901
- Verified Reactivity
- Human, Mouse, Rat
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
WB - Quality tested
ICC - Reported in the literature, not verified in house
- Recommended Usage
Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested use of this reagent is 2.0 - 10 ?g per ml. It is recommended that the reagent be titrated for optimal performance for each application.
- Application References
(PubMed link indicates BioLegend citation) -
- Battle D, et al. 2007. J Biol Chem. 282(38):27953 (WB, ICC)
- Product Citations
-
- Bizen N, et al. 2022. Cell Death Differ. . PubMed
- RRID
- AB_2810755 (BioLegend Cat. No. 862901) AB_2810756 (BioLegend Cat. No. 862902)
- Structure
- Gemin 2 is a 280 amino acid protein with an apparent molecular mass of ~ 32 kD.
- Distribution
-
Tissue Distribution: Brain, skeletal muscle, gallbladder, and testis
Cellular Distribution: Nuclear and cytosol
- Function
- Gemin 2 is a component of the SMN complex that is essential for the formation of snRNP complexes. It organizes 5 Sm proteins into a partial ring for snRNA binding.
- Interaction
- Gemin 2 binds to SM proteins and is found in complex with other SMN/GEMIN proteins.
- Cell Type
- Neurons
- Biology Area
- Chromatin Remodeling/Epigenetics, Neurodegeneration, Neuroscience, Synaptic Biology, Transcription Factors
- Antigen References
-
- Battle D, et al. 2007. J Biol Chem. 282(38):27953
- Gupta K, et al. 2015. J Biol Chem. 290(33):20185
- Gene ID
- 8487 View all products for this Gene ID 66603 View all products for this Gene ID 84404 View all products for this Gene ID
- UniProt
- View information about Gemin 2 on UniProt.org
