Purified anti-E1 Ubiquitin Activating Enzyme Antib
- 产品名称：
- Purified anti-E1 Ubiquitin Activating Enzyme Antib
- 产品类别：
- 抗体
- 产品编号：
- 932002
- 产品应用：
- 932002
- Verified Reactivity
- Human, Mouse
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- Mixture of human and mouse E1 protein.
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
WB - Quality tested
ICC - Verified
- Recommended Usage
Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested use of this reagent is 0.25 - 2.0 ?g per ml. For immunocytochemistry, the suggested use of this reagent is 1.0 - 5.0 ?g per ml. It is recommended that the reagent be titrated for optimal performance for each application.
- Application References
(PubMed link indicates BioLegend citation) -
- Salvat C, et al. 2000. Eur. J. Biochem. 267:3712.
- RRID
- AB_2565603 (BioLegend Cat. No. 932002)
- Structure
- 1058 amino acids with a predicted molecular weight of approximately 118 kD.
- Distribution
-
Ubiquitous, Eukaryotic cells.
- Function
- This protein catalyzes the first step in ubiquitin conjugation to mark cellular proteins for degradation.
- Interaction
- GAN.
- Biology Area
- Cell Biology, DNA Repair/Replication, Neurodegeneration, Neuroscience, Protein Trafficking and Clearance, Signal Transduction, Transcription Factors, Ubiquitin/Protein Degradation
- Molecular Family
- Protein Modifiers
- Antigen References
-
1. Xu W, et al. 2013. Curr. Pharm. Des. 18:3201.
2. Neutzner M, et al. 2012. Essays Biochem. 52:37.
3. Schulman BA, et al. 2009. Nat. Rev. Mol. Cell Biol. 10:319.
4. Salvat C, et al. 2000. Eur. J. Biochem. 267:3712.
- Gene ID
- 7317 View all products for this Gene ID
- UniProt
- View information about E1 Ubiquitin Activating Enzyme on UniProt.org
