Alexa Fluor® 594 anti-E1 Ubiquitin Activating
- 产品名称：
- Alexa Fluor® 594 anti-E1 Ubiquitin Activating
- 产品类别：
- 抗体
- 产品编号：
- 679404
- 产品应用：
- 679404
- Verified Reactivity
- Human, Mouse
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- Mixture of human and mouse E1 protein.
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography and conjugated with Alexa Fluor? 594 under optimal conditions.
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
ICC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunocytochemistry. For immunocytochemistry, a concentration range of 0.1 - 10 μg/ml is recommended. It is recommended that the reagent be titrated for optimal performance for each application.
* Alexa Fluor? 594 has an excitation maximum of 590 nm, and a maximum emission of 617 nm.
Alexa Fluor? and Pacific Blue? are trademarks of Life Technologies Corporation.
View full statement regarding label licenses - Application References
(PubMed link indicates BioLegend citation) -
- Salvat C, et al. 2000. Eur. J. Biochem. 267:3712.
- RRID
- AB_2566181 (BioLegend Cat. No. 679404)
- Structure
- 1058 amino acids with a predicted molecular weight of approximately 118 kD.
- Distribution
-
Ubiquitous, Eukaryotic cells.
- Function
- This protein catalyzes the first step in ubiquitin conjugation to mark cellular proteins for degradation.
- Interaction
- GAN.
- Biology Area
- Cell Biology, DNA Repair/Replication, Signal Transduction, Transcription Factors, Ubiquitin/Protein Degradation
- Molecular Family
- Protein Modifiers
- Antigen References
-
1. Xu W, et al. 2013. Curr. Pharm. Des. 18:3201.
2. Neutzner M, et al. 2012. Essays Biochem. 52:37.
3. Schulman BA, et al. 2009. Nat. Rev. Mol. Cell Biol. 10:319.
4. Salvat C, et al. 2000. Eur. J. Biochem. 267:3712.
- Gene ID
- 7317 View all products for this Gene ID
- UniProt
- View information about E1 Ubiquitin Activating Enzyme on UniProt.org
