Direct-Blot™ HRP anti-Histone H3 Acetylated -上海雅吉生物科技有限公司

规格	价格	库存
25µL	￥ 1488	1

Product Details

Verified Reactivity: Human, Mouse
Antibody Type: Monoclonal
Host Species: Rat
Immunogen: Histone H3 K9ac peptide
Formulation: This antibody is provided in 50% glycerol in aqueous buffered solutions with preservatives.
Preparation: The antibody was purified by affinity chromatography and conjugated with HRP under optimal conditions.
Concentration: Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
Storage & Handling: Upon receipt, the antibody solution should be stored undiluted at -20°C, and protected from prolonged exposure to light.
Application: WB -?Quality tested
Recommended Usage: Each lot of this antibody is quality control tested by western blotting. For western blotting, the suggested use of this reagent is 1:1000?- 1:2000?dilution. It is recommended that the reagent be titrated for optimal performance for each application.
Application Notes: This clone is not recommended for ChIP (Chromatin Immunoprecipitation) assays (as determined by in-house testing).
RRID: AB_2861072 (BioLegend Cat. No. 698407) AB_2861073 (BioLegend Cat. No. 698408)

Structure: Histone H3 is a 134 aa protein with a predicted molecular weight of 15.4 kD. The subunit is comprised of a histone fold, an αN-helix main globular domain and a large N-terminal tail harboring residues subject to multiple types of post-translational.
Distribution: Nucleus
Function: Histone acetylation is generally associated with activation of gene expression, nucleosomal redistribution, and histone deposition. One consequence of this modification is the alteration of chromatin structure to facilitate recruitment of transcription factors. Additionally, acetyl-lysine modification is also used as binding site for proteins containing bromodomains, resulting in their recruitment to the modified histones.
Interaction: Histones 2A, 2B, 4, HDAC
Biology Area: Cell Biology, Chromatin Remodeling/Epigenetics
Antigen References: 1. Zhang,?et al. 2017.?Nat. Commun.?8: 14799.
2. Kanda M,?et al. 2016.?Proc. Natl. Acad. Sci. USA?113: E3394.
3. Bellet MM,?et al. 2013.?Proc. Natl. Acad. Sci. USA?9: 3333.
4. Li B,?et al.?2016.?Sci. Rep.?6: 26542.
5.?Li D,?et al. 2014,?Mol. Cancer. 13:26.
Gene ID: 8350 View all products for this Gene ID
UniProt: View information about Histone H3 Acetylated Lys9 on UniProt.org