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Purified anti-human CD360 (IL-21R) Antibody
产品名称:
Purified anti-human CD360 (IL-21R) Antibody
产品类别:
抗体
产品编号:
347802
产品应用:
347802
[价格]
规格 价格 库存
100µg ¥ 3180 1

产品详情

Product Details

Verified Reactivity
Human, Cynomolgus, Rhesus
Reported Reactivity
African Green, Baboon
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
IL-21R transfected Ba/F3 cells
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography.
Concentration
0.5 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C.
Application

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 2.0 ?g per 106 cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.

Application References

(PubMed link indicates BioLegend citation)
  1. Rodrigues-Bayona B, et al. 2012. J. Immunol. 188:1578. PubMed
RRID
AB_2044031 (BioLegend Cat. No. 347802)

Antigen Details

Structure
Single pass type I membrane protein, extracellular WSXWS-containing cytokine-binding domain, intracellular Box1 and Box2 domains
Distribution

B cells, various levels on NK cells and T cells

Ligand/Receptor
IL-21
Cell Type
B cells, NK cells, T cells, Tregs
Biology Area
Immunology, Innate Immunity
Molecular Family
CD Molecules, Cytokine/Chemokine Receptors
Antigen References

1. Parish-Novak J, et al. 2000. Nature 408:57.
2. Ozaki K, et al. 2000. Proc Natl. Acad. Sci. USA. 97:11439.
3. Dumoutier L, et al. 2000. Proc Natl. Acad. Sci. USA. 97:10144.
4. Asao H, et al. 2001. J. Immunol. 167:1.
5. Parish-Novak J, et al. 2002. J. Leukocyte Biol. 72:856.
6. de Torero D, et al. 2006. Blood 107:3708.
7. Davis ID, et al.2007. Clin Cancer Res. 13:6926.
8. Nurieva R, et al. 2007. Nature 448:4416.

Gene ID
50615 View all products for this Gene ID
UniProt
View information about CD360 on UniProt.org

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