APC anti-human CD360 (IL-21R) Antibody -上海雅吉生物科技有限公司

规格	价格	库存
25tests	￥ 2064	1

Product Details

Verified Reactivity

Human, Cynomolgus, Rhesus

Reported Reactivity

African Green, Baboon

Antibody Type

Monoclonal

Host Species

Mouse

Immunogen

IL-21R transfected Ba/F3 cells

Formulation

Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)

Preparation

The antibody was purified by affinity chromatography and conjugated with APC under optimal conditions.

Concentration

Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)

Storage & Handling

The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.

Application

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 ?l per million cells in 100 ?l staining volume or 5 ?l per 100 ?l of whole blood.

Excitation Laser

Red Laser (633 nm)

Application References (PubMed link indicates BioLegend citation)

Rodrigues-Bayona B, et al. 2012. J. Immunol. 188:1578. PubMed

Product Citations

Kotlarz D, et al. 2013. J Exp Med. 210:433. PubMed
Spolski R et al. 2019. Elife. 8 pii: e45501. PubMed

RRID

AB_2123989 (BioLegend Cat. No. 347807) AB_2123988 (BioLegend Cat. No. 347808)

Antigen Details

Structure: Single pass type I membrane protein, extracellular WSXWS-containing cytokine-binding domain, intracellular Box1 and Box2 domains
Distribution: B cells, various levels on NK cells and T cells
Ligand/Receptor: IL-21
Cell Type: B cells, NK cells, T cells, Tregs
Biology Area: Immunology, Innate Immunity
Molecular Family: CD Molecules, Cytokine/Chemokine Receptors
Antigen References: 1. Parish-Novak J, et al. 2000. Nature 408:57.
2. Ozaki K, et al. 2000. Proc Natl. Acad. Sci. USA. 97:11439.
3. Dumoutier L, et al. 2000. Proc Natl. Acad. Sci. USA. 97:10144.
4. Asao H, et al. 2001. J. Immunol. 167:1.
5. Parish-Novak J, et al. 2002. J. Leukocyte Biol. 72:856.
6. de Torero D, et al. 2006. Blood 107:3708.
7. Davis ID, et al.2007. Clin Cancer Res. 13:6926.
8. Nurieva R, et al. 2007. Nature 448:4416.
Gene ID: 50615 View all products for this Gene ID
UniProt: View information about CD360 on UniProt.org

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