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Purified anti-Connexin 43, 247-382 Antibody
产品名称:
Purified anti-Connexin 43, 247-382 Antibody
产品类别:
抗体
产品编号:
850001
产品应用:
850001
[价格]
规格 价格 库存
25µg ¥ 1416 1

产品详情

Product Details

Verified Reactivity
Human, Mouse
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
KLH-conjugated peptide corresponding to amino acids 247-382 of Connexin 43
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography.
Concentration
0.5 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C.
Application

WB - Quality tested
IHC-P - Verified

Recommended Usage

Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested use of this reagent is 1 to 5 ?g per ml.?For immunohistochemical staining on formalin-fixed paraffin-embedded tissue sections, the suggested use of this reagent is 5 ?g per ml. It is recommended that the reagent be titrated for optimal performance for each application.

RRID
AB_2721730 (BioLegend Cat. No. 850001) AB_2721731 (BioLegend Cat. No. 850002)

Antigen Details

Structure
Connexin 43 (GJA1) is a 382 amino acid protein with a molecular mass of 43 kD.
Distribution

Tissue distribution: expressed in most tissues, enriched in brain, endocrine, muscle, bone marrow, immune System, ovaries, testes, and Skin.
Cellular distribution: plasma membrane, cytosol, mitochondria, golgi apparatus, cytoskeleton and endoplasmic reticulum membrane.

Function
Connexin 43 plays a role in cell-to-cell communication by forming channels or gap junctions between cells. It allows for the transport of nutrients, charged particles (ions), and other small molecules that carry necessary communication signals between cells.
Biology Area
Cell Biology, Neuroscience, Neuroscience Cell Markers
Antigen References
  1. Grek CL, et al. 2016. Cancer Lett. 374(1):117
  2. Lilly E, et al. 2016. Semin Cell Dev Biol. 50:4
  3. Michela P, et al. 2015. Eur J Pharmacol. 768:71
Gene ID
2697 View all products for this Gene ID
UniProt
View information about Connexin 43 247-382 on UniProt.org

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